anti-Pferd Ubiquitin-Conjugating Enzyme E2D 2 Antikörper für Western Blotting

Recommended Ubiquitin-Conjugating Enzyme E2D 2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Antikörper
  • E2(17)KB2
  • PUBC1
  • UBC4
  • UBC4/5
  • UBCH5B
  • ube2d2
  • Ube2d2
  • zgc:55886
  • E217kB
  • Ubc2e
  • ubiquitin conjugating enzyme E2 D2
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
  • ubiquitin-conjugating enzyme E2D 2
  • UBE2D2
  • ube2d2
  • Ube2d2
Epitop
N-Term
19
11
8
4
4
4
3
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
101
48
47
8
7
6
5
5
5
5
3
3
3
2
1
1
1
Wirt
Kaninchen
73
28
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
83
38
16
13
12
4
2
2
1
Optionen
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Bilder

Produktnummer ABIN2775672
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0809376 ABIN2775675 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
3.0809376 ABIN2775673 IHC WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN203474 IHC IHC (p) WB Rabbit IgG AA 91-140 Anmelden zum Anzeigen Polyclonal 0
1 ABIN468829 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN468830 WB Rabbit AA 36-85 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Antikörper
Epitop N-Term
(19), (11), (8), (4), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
(101), (48), (47), (8), (7), (6), (5), (5), (5), (5), (3), (3), (3), (2), (1), (1), (1)
Wirt Kaninchen
(73), (28)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(83), (38), (16), (13), (12), (4), (2), (2), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985811.
Sequenz ALKRIHKELN DLARDPPAQC SAGPVGDDMF HWQATIMGPN DSPYQGGVFF
Homologie Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against UBE2D2. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D2

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung UBE2D2 (UBE2D2 Antibody Abstract)
Hintergrund The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Protein Interaction Partner: RNF26, CHFR, RBX1, DZIP3, UBA1, UBC, TRAF6, BIRC7, anapc11, ZNRF1, RNF146, MID1, MDM2, BIRC3, FZR1, ITCH, HRD1, CUL3, XIAP, MARCH7, RNF25, UBE2D2, RNF130, UBA6, CBLC, PARK2, TRIM21, KCMF1, RNF135, MUL1, MDM4, TRIM23, STUB1, CBL, UBTD1, RNF38, UBI4, RFFL,
Protein Size: 147
Molekulargewicht 17 kDa
Gen-ID 7322
NCBI Accession NM_003339, NP_003330
UniProt P62837
Pathways Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 147 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Guinn, Bland, Lodi, Liggins, Tobal, Petters, Wells, Banham, Mufti: "Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia." in: Biochemical and biophysical research communications, Vol. 335, Issue 4, pp. 1293-304, 2005

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) (N-Term) antibody (ABIN2775672) WB Suggested Anti-UBE2D2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Po...
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) (N-Term) antibody (ABIN2775672) Lanes: 1: 40ng HIS-UBE2D1 protein 2: 40ng HIS-UBE2D2 protein 3: 40ng HIS-UBE2D3 pro...