UBE2D2 Antikörper (N-Term)

Produktnummer ABIN6243331

Produktdetails anti-UBE2D2 Antikörper

Target: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Bindungsspezifität: AA 44-76, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2D2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBE2D2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-76 amino acids from the N-terminal region of human UBE2D2.

Klon: RB49628

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu UBE2D2

Target: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Andere Bezeichnung: UBE2D2 (UBE2D2 Produkte)

Synonyme: E2(17)KB2 antikoerper, PUBC1 antikoerper, UBC4 antikoerper, UBC4/5 antikoerper, UBCH5B antikoerper, 1500034D03Rik antikoerper, Ubc2e antikoerper, Ube2d2 antikoerper, ubc4 antikoerper, ube2d2 antikoerper, zgc:55886 antikoerper, E217kB antikoerper, ubiquitin conjugating enzyme E2 D2 antikoerper, ubiquitin-conjugating enzyme E2D 2A antikoerper, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) antikoerper, ubiquitin-conjugating enzyme E2D 2 antikoerper, ubiquitin conjugating enzyme E2 D3 antikoerper, UBE2D2 antikoerper, Ube2d2a antikoerper, ube2d2 antikoerper, Ube2d2 antikoerper, UBE2D3 antikoerper

Hintergrund: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

Molekulargewicht: 16735

UniProt: P62837

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades