Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2775673, Anbieter: Anmelden zum Anzeigen
Antigen
  • E2(17)KB2
  • PUBC1
  • UBC4
  • UBC4/5
  • UBCH5B
  • 1500034D03Rik
  • Ubc2e
  • Ube2d2
  • ubc4
  • ube2d2
  • zgc:55886
  • E217kB
  • ubiquitin conjugating enzyme E2 D2
  • ubiquitin-conjugating enzyme E2D 2A
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
  • ubiquitin-conjugating enzyme E2D 2
  • UBE2D2
  • Ube2d2a
  • ube2d2
  • Ube2d2
Epitop
Middle Region
18
10
9
4
3
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
88
41
40
8
7
6
5
5
5
5
3
3
3
2
1
1
1
1
Wirt
Kaninchen
60
28
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
72
29
13
12
9
3
2
1
Optionen
Hersteller
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human UBE2D2
Sequenz SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against UBE2D2. It was validated on Western Blot and immunohistochemistry.
Reinigung Protein A purified
Andere Bezeichnung UBE2D2 (UBE2D2 Antibody Abstract)
Hintergrund The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001).[supplied by OMIM].
Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Protein Interaction Partner: RNF26, CHFR, RBX1, DZIP3, UBA1, UBC, TRAF6, BIRC7, anapc11, ZNRF1, RNF146, MID1, MDM2, BIRC3, FZR1, ITCH, HRD1, CUL3, XIAP, MARCH7, RNF25, UBE2D2, RNF130, UBA6, CBLC, PARK2, TRIM21, KCMF1, RNF135, MUL1, MDM4, TRIM23, STUB1, CBL, UBTD1, RNF38, UBI4, RFFL,
Protein Size: 547
Molekulargewicht 60 kDa
Gen-ID 7322
NCBI Accession NM_018018, NP_003330
UniProt P62837
Pathways Activation of Innate immune Response, Toll-Like Receptors Cascades
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 547 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) (Middle Region) antibody (ABIN2775673) WB Suggested Anti-UBE2D2 Antibody Titration: 1.25ug/ml
Positive Control:...
Produkt verwendet in: Desforges, Lacey, Glazier, Greenwood, Mynett, Speake, Sibley: "SNAT4 isoform of system A amino acid transporter is expressed in human placenta." in: American journal of physiology. Cell physiology, Vol. 290, Issue 1, pp. C305-12, 2005 (PubMed).

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