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SEMA5B encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. Zusätzlich bieten wir Ihnen SEMA5B Proteine (10) und und viele weitere Produktgruppen zu diesem Protein an.
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SEMA5B could possibly serve as a candidate gene for alterations associated with asbestos exposure.
Sema5B regulates the development and maintenance of synapse size and number in hippocampal neurons.
This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene.
, sema G
, semaphorin 5B