anti-Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Antikörper

The protein encoded by PTP4A2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen Protein tyrosine Phosphatase Type IVA, Member 2 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTP4A2 19244 O70274
PTP4A2 85237 Q6P9X4
PTP4A2 8073 Q12974
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Top anti-Protein tyrosine Phosphatase Type IVA, Member 2 Antikörper auf antikoerper-online.de

Showing 10 out of 68 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC(P): Human Prostatic Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB PTP4A2 Antibody (Center) (ABIN390820) western blot analysis in NCI-H460 cell line lysates (35 µg/lane).This demonstrates the PTP4A2 antibody detected the PTP4A2 protein (arrow). Formalin-fixed and paraffin-embedded human prostate carcinoma with PTP4A2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane. Western blot analysis in NCI-H460 cell line lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$390.50
Details
Human Maus Unkonjugiert ELISA, WB Western Blot: PRL-2/PTP4A2 Antibody (5B6F4) [NBP2-37315] - Western blot analysis using PTP4A2 mAb against human PTP4A2 recombinant protein. (Expected MW is 37.5 kDa) Western Blot: PRL-2/PTP4A2 Antibody (5B6F4) [NBP2-37315] - Western blot analysis using PTP4A2 mAb against HEK293 (1) and PTP4A2 (AA: 58-162)-hIgGFc transfected HEK293 (2) cell lysate. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged PTP4A2 is 0.03 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert EIA, WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
$517.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
Details

PTP4A2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Protein tyrosine Phosphatase Type IVA, Member 2 Antikörper

  1. Human Monoclonal PTP4A2 Primary Antibody für ELISA, WB - ABIN1724901 : Hardy, Wong, Muller, Park, Tremblay: Overexpression of the protein tyrosine phosphatase PRL-2 correlates with breast tumor formation and progression. in Cancer research 2010 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Protein tyrosine Phosphatase Type IVA, Member 2 Interaktionspartner

Mouse (Murine) Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Interaktionspartner

  1. a critical role for PRL2 phosphatase in mediating Notch (zeige NOTCH1 Antikörper) and c-Kit (zeige KIT Antikörper) signals in early T cell progenitors, is reported.

  2. Oncogenic PRL-2 controls tumor growth by modulating intracellular magnesium levels through binding with the CNNM3 (zeige CNNM3 Antikörper) magnesium transporter.

  3. PTP4A2 plays critical roles in regulating hematopoietic stem cell self-renewal and mediating SCF (zeige KITLG Antikörper)/KIT signaling.

  4. PRL2 promotes Kit-mediated PI3K/Akt signaling by reducing the level of PTEN that normally antagonizes the pathway.

  5. Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin (zeige TNS1 Antikörper) Homologue Deleted on Chromosome 10) and activating Akt (zeige AKT1 Antikörper) protein

Human Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Interaktionspartner

  1. identified a critical role for PRL2 phosphatase in the proliferation and survival of human AML cells. Further, we demonstrated that PRL2 is essential for the leukemogenic potential of AML1-ETO9a in vivo

  2. Our findings highlight the important role of miR (zeige MLXIP Antikörper)-29c in regulating CRC (zeige CALR Antikörper) EMT (zeige ITK Antikörper) via GSK-3b/b-catenin signaling by targeting GNA13 (zeige GNA13 Antikörper) and PTP4A and provide new insights into the metastatic basis of colorectal cancer

  3. PTP4A2 expression is correlated with overall survival in progestin receptor-positive breast carcinomas.

  4. Results suggest that TRP32 (zeige TXNL1 Antikörper) maintains the reduced state of PRL (zeige PRL Antikörper) and thus regulates the biological function of PRL (zeige PRL Antikörper).

  5. Studies indicate that PRL-1 (zeige PLRG1 Antikörper) and PRL-2 and PRL-3 are oncogenes and belong to the few phosphatases that lead to the development of cancer.

  6. Results suggest a model in which PRL-2 promotes cell migration and invasion through an ERK1/2-dependent signaling pathway.

  7. PRL-2 plays an important role in lung cancer and can be a biomarker of lung cancer, substituting for the function of other PRLs.

  8. Overexpression of the protein tyrosine phosphatase (zeige ACP1 Antikörper) PRL-2 correlates with breast tumor formation and progression.

  9. Mouse pre-B-cells transfected with human PRL-2 had higher growth responses to Epo (zeige EPO Antikörper) or IL-3 (zeige IL-3 Antikörper), shorter cell cycle, less Epo (zeige EPO Antikörper) requirement for survival, more cell migration, less cell adhesion, change to an immature cell morphology, & more Bmi-1 (zeige BMI1 Antikörper) expression.

  10. PRL-2 can promote cell adhesion and invasion activity of human hepatocellular carcinoma cells.

Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Genbezeichner und Symbole assoziert mit PTP4A2

  • protein tyrosine phosphatase type IVA, member 2b (ptp4a2b) Antikörper
  • protein tyrosine phosphatase 4a2 (ptp4a2) Antikörper
  • protein tyrosine phosphatase type IVA, member 2 (PTP4A2) Antikörper
  • protein tyrosine phosphatase type IVA, member 2 L homeolog (ptp4a2.L) Antikörper
  • protein tyrosine phosphatase type IVA, member 2 (ptp4a2) Antikörper
  • protein tyrosine phosphatase 4a2 (Ptp4a2) Antikörper
  • protein tyrosine phosphatase type IVA, member 2 (Ptp4a2) Antikörper
  • HH7-2 Antikörper
  • HH13 Antikörper
  • HU-PP-1 Antikörper
  • MGC53390 Antikörper
  • MGC80084 Antikörper
  • MGC132077 Antikörper
  • OV-1 Antikörper
  • PRL-2 Antikörper
  • PRL2 Antikörper
  • ptp-IV1a Antikörper
  • ptp-IV1b Antikörper
  • PTP4A Antikörper
  • ptp4a2 Antikörper
  • PTPCAAX2 Antikörper
  • wu:fc05f09 Antikörper
  • wu:fi84b06 Antikörper
  • zgc:101724 Antikörper

Bezeichner auf Proteinebene für PTP4A2

PRL-2 , fc05f09 , protein tyrosine phosphatase type IVA 2 , protein tyrosine phosphatase 4a2 , protein tyrosine phosphatase type IVA, member 2 , protein-tyrosine phosphatase 4a2 , protein-tyrosine phosphatase of regenerating liver 2 , PTP(CAAXII) , phosphatase of regenerating liver 2 , protein tyrosine phosphatase IVA , protein tyrosine phosphatase IVA2

GENE ID SPEZIES
334483 Danio rerio
379932 Xenopus laevis
419649 Gallus gallus
443874 Xenopus laevis
454687 Pan troglodytes
549961 Xenopus (Silurana) tropicalis
609835 Canis lupus familiaris
19244 Mus musculus
85237 Rattus norvegicus
8073 Homo sapiens
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