wu:fc05f09 antikoerper, wu:fi84b06 antikoerper, zgc:101724 antikoerper, MGC53390 antikoerper, MGC80084 antikoerper, MGC132077 antikoerper, PTP4A2 antikoerper, ptp4a2 antikoerper, Prl-2 antikoerper, HH13 antikoerper, HH7-2 antikoerper, HU-PP-1 antikoerper, OV-1 antikoerper, PRL-2 antikoerper, PRL2 antikoerper, PTP4A antikoerper, PTPCAAX2 antikoerper, ptp-IV1a antikoerper, ptp-IV1b antikoerper, protein tyrosine phosphatase type IVA, member 2b antikoerper, protein tyrosine phosphatase 4a2 antikoerper, protein tyrosine phosphatase type IVA, member 2 antikoerper, protein tyrosine phosphatase type IVA, member 2 L homeolog antikoerper, ptp4a2b antikoerper, ptp4a2 antikoerper, PTP4A2 antikoerper, ptp4a2.L antikoerper, Ptp4a2 antikoerper
Hintergrund
PTP4A2,HH13,HH7-2,HU-PP-1,OV-1,PRL-2,PRL2,PTP4A,PTPCAAX2,ptp-IV1a,ptp-IV1b,The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.