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Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal PARP10 Primary Antibody für IF, IHC - ABIN151587
Shahrour, Nicolae, Edvardson, Ashhab, Galvan, Constantin, Abu-Libdeh, Moldovan, Elpeleg: PARP10 deficiency manifests by severe developmental delay and DNA repair defect. in Neurogenetics 2016
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PARP10 expression decreased upon fasting, a condition that is characterized by increases in mitochondrial biogenesis. Finally, lower PARP10 expression is associated with increased fatty acid oxidation
ARTD10 plays roles in immunity, metabolism ,apoptosis and DNA damage repair. [review]
PARP10 binding to PCNA is required for translesion DNA synthesis.
study results show that the interaction between PARP10 and NS1 of H5N1 avian influenza virus can change cell cycle, and PARP10 can affect virus replication
novel PARP enzyme involved in the control of cell proliferation
Overexpression of PARP10 results in loss of cell viability, although down-expression by short hairpin RNA leads to delayed G1 progression and concomitant cell death.
alternative catalytic mechanism for PARP10 compared to PARP1 in which the acidic target residue of the substrate functionally substitutes for the catalytic glutamate by using substrate-assisted catalysis to transfer ADP-ribose
Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005
ADP-ribosyltransferase diphtheria toxin-like 10
, poly [ADP-ribose] polymerase 10
, poly (ADP-ribose) polymerase family, member 10
, poly [ADP-ribose] polymerase 10-like