Histidine Rich Calcium Binding Protein (HRC) ELISA Kits

HRC encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. Zusätzlich bieten wir Ihnen HRC Antikörper (25) und und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus HRC HRC 15464  
Anti-Ratte HRC HRC 292905  
HRC 3270 P23327
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.123 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$589.47
Details

Weitere ELISA Kits für HRC Interaktionspartner

Mouse (Murine) Histidine Rich Calcium Binding Protein (HRC) Interaktionspartner

  1. The minimal KEKE motif of TRN (zeige TNPO1 ELISA Kits) involved in the interactions with CSQ2, HRC and RyR2 (zeige RYR2 ELISA Kits) within the Ca2 (zeige CA2 ELISA Kits)+ release units of cardiac sarcoplasmic reticulum has been defined.

  2. While CASQ2 stabilizes RyR2 (zeige RYR2 ELISA Kits) rendering it refractory in the diastolic phase, HRC enhances RyR2 (zeige RYR2 ELISA Kits) activity facilitating RyR2 (zeige RYR2 ELISA Kits) recovery from refractoriness.

  3. Ablation of HRC is associated with poorly regulated SR Ca(2 (zeige CA2 ELISA Kits)+)-cycling, and severe pathology under pressure-overload stress, suggesting an essential role of HRC in maintaining the integrity of cardiac function.

  4. Results identify the HRC enhancer as the first MEF2 (zeige MEF2C ELISA Kits)-dependent, CArG-motif-independent transcriptional target in smooth muscle and represent the first analysis of the transcriptional regulation of a sarcoplasmic reticulum gene in vivo.

  5. alterations in expression levels of HRC are associated with impaired cardiac SR Ca homeostasis and contractile function.

  6. HRC may be an integral regulatory protein involved in cardiac muscle SR Ca uptake and Ca homeostasis

  7. The exaggerated response of HRC knockout mice to the induction of cardiac hypertrophy is consistent with a regulatory role for HRC in calcium handling in vivo.

  8. Histidine-rich Ca-binding protein may play a key role in the regulation of SR Ca cycling through its direct interactions with SERCA2 and triadin, mediating a fine cross talk between SR Ca uptake and release in the heart.

Human Histidine Rich Calcium Binding Protein (HRC) Interaktionspartner

  1. this study demonstrates a role of HRC in promoting hepatocellular carcinoma (HCC) growth, besides its role in inducing HCC metastasis, and highlights HRC as a promising intervention target for HCC.

  2. Up-regulation of histidine-rich calcium binding protein promotes tumor metastasis in hepatocellular carcinoma and is mediated by SATB1 (zeige SATB1 ELISA Kits).

  3. The S96A HRC mutation disrupts the Ca2 (zeige CA2 ELISA Kits)+ -microdomain around the RyR2 (zeige RYR2 ELISA Kits), as it alters the Ca2 (zeige CA2 ELISA Kits)+ -dependent association of RyR2 (zeige RYR2 ELISA Kits) and HRC.

  4. findings suggest that aberrant sarcoplasmic reticulum Ca2 (zeige CA2 ELISA Kits)+ release and increased susceptibility to delayed afterdepolarizations underlie triggered arrhythmic activity in Ala96 HRC carriers

  5. Results identify the HRC enhancer as the first MEF2 (zeige MEF2A ELISA Kits)-dependent, CArG-motif-independent transcriptional target in smooth muscle and represent the first analysis of the transcriptional regulation of a sarcoplasmic reticulum gene in vivo.

  6. alterations in expression levels of HRC are associated with impaired cardiac SR Ca homeostasis and contractile function.

  7. Histidine-rich Ca-binding protein may play a key role in the regulation of SR Ca cycling through its direct interactions with SERCA2 and triadin, mediating a fine cross talk between SR Ca uptake and release in the heart.

  8. The Ser96Ala genetic variant of HRC is associated with life-threatening ventricular arrhythmias in idiopathic DCM and may serve as an independent predictor of susceptibility to arrhythmogenesis in the setting of DCM.

HRC Antigen-Profil

Beschreibung des Gens

This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR.

Genbezeichner und Symbole assoziert mit HRC

  • histidine rich calcium binding protein (HRC) Antikörper
  • histidine rich calcium binding protein (Hrc) Antikörper
  • DKFZp468J236 Antikörper

Bezeichner auf Proteinebene für HRC

histidine rich calcium binding protein , histidine-rich calcium-binding protein , sarcoplasmic reticulum histidine-rich calcium-binding protein , histidine rich calcium-binding protein

GENE ID SPEZIES
456413 Pan troglodytes
484386 Canis lupus familiaris
617610 Bos taurus
718647 Macaca mulatta
100049576 Equus caballus
100171720 Pongo abelii
100594612 Nomascus leucogenys
15464 Mus musculus
292905 Rattus norvegicus
3270 Homo sapiens
100009049 Oryctolagus cuniculus
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