anti-Growth Differentiation Factor 15 (GDF15) Antikörper

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Zusätzlich bieten wir Ihnen GDF15 Kits (86) und GDF15 Proteine (34) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GDF15 9518 Q99988
GDF15 23886 Q9Z0J7
GDF15 29455 Q9Z0J6
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Top anti-GDF15 Antikörper auf antikoerper-online.de

Showing 10 out of 303 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-GDF15 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>PANC1 cell lysate WB Suggested Anti-GDF15 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: PANC1 cell lysate <br /> GDF15 is strongly supported by BioGPS gene expression data to be expressed in Human PANC1 cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185465 (0.1µg/ml) staining of Human Prostate lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of GDF15 expression in HepG2 (A), NIH3T3 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Maus Kaninchen Unkonjugiert ELISA, WB Western blot using affinity purified anti-mouse NAG-1/GDF15 antibody. The blot shows detection of recombinant MBP-NAG-1 fusion protein (60 kDa) purified from E.coli (lane 1), yeast cell lysate expressing SUMO-mouse NAG-1 (42 kDa) (lane 2), and R&D human NAG-1 monomer purified from CHO-K1 cells (14 kDa) (lane 3). All lysates were run under reducing conditions. Primary antibody was used at a 1:1000 dilution in TBS containg 1% BSA and 0.2% Tween, and reacted overnight at 4°C. Nag-1 was detected using a 1:40,000 dilution of peroxidase conjugated Gt-a-Rabbit antibody (611-103-122) in Blocking Buffer for Fluorescent Western Blotting (MB-070) for 30 min at room temperature. Molecular weight estimation was made by comparison to prestained MW markers. Image was captured using the BioRad Versadoc™ 4000MP Imaging System. Other detection systems will yield similar results. Western blot using  affinity purified anti-mouse NAG-1/GDF15 antibody. The blot shows detection of recombinant MBP-NAG-1 fusion protein (60 kDa) purified from E.coli (lane 1); yeast cell lysate expressing SUMO-mouse NAG-1 (42 kDa) (lane 2), and R&D human NAG-1 monomer purified from CHO-K1 cells (14 kDa) (lane 3). All lysates were run under reducing conditions. Primary antibody was used at a 1:1000 dilution in TBS containg 1% BSA and 0.2% Tween, and reacted overnight at 4°C. Nag-1 was detected using a 1:40,000 dilution of peroxidase conjugated Gt-a-Rabbit antibody  in Blocking Buffer for Fluorescent Western Blotting (ABIN925618) for 30 min at room temperature. Molecular weight estimation was made by comparison to prestained MW markers. Image was captured using the BioRad 4000MP Imaging System. Other detection systems will yield similar results. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: GDF-15 Antibody [NBP1-81050] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Western Blot: GDF-15 Antibody [NBP1-81050] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from 293/HepG2 cells, using GDF15 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Maus Kaninchen Unkonjugiert ELISA, WB Western blot using affinity purified anti-Mouse NAG-1/GDF15 antibody. The blot shows detection of recombinant MBP-NAG-1 fusion protein (60 kDa) purified from E.coli (lane 1), yeast cell lysate expressing SUMO-mouse NAG-1 (42 kDa) (lane 2), and R&D human NAG-1 monomer purified from CHO-K1 cells (14 kDa) (lane 3). All lysates were run under reducing conditions. Primary antibody was used at a 1:1000 dilution in TBS containg 1% BSA and 0.2% Tween, and reacted overnight at 4°C. Nag-1 was detected using a 1:40,000 dilution of peroxidase conjugated Gt-a-Rabbit antibody (611-103-122) in Blocking Buffer for Fluorescent Western Blotting (MB-070) for 30 min at room temperature. Molecular weight estimation was made by comparison to prestained MW markers. Image was captured using the BioRad Versadoc™ 4000MP Imaging System. Other detection systems will yield similar results. Western blot using  affinity purified anti-Mouse NAG-1/GDF15 antibody. The blot shows detection of recombinant MBP-NAG-1 fusion protein (60 kDa) purified from E.coli (lane 1); yeast cell lysate expressing SUMO-mouse NAG-1 (42 kDa) (lane 2), and R&D human NAG-1 monomer purified from CHO-K1 cells (14 kDa) (lane 3). All lysates were run under reducing conditions. Primary antibody was used at a 1:1000 dilution in TBS containg 1% BSA and 0.2% Tween, and reacted overnight at 4°C. Nag-1 was detected using a 1:40,000 dilution of peroxidase conjugated Gt-a-Rabbit antibody  in Blocking Buffer for Fluorescent Western Blotting (ABIN925618) for 30 min at room temperature. Molecular weight estimation was made by comparison to prestained MW markers. Image was captured using the BioRad 4000MP Imaging System. Other detection systems will yield similar results. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p) Immunohistochemistry-Paraffin: GDF-15 Antibody [NBP1-02492] - Staining of human testis. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Immunohistochemistry-Paraffin: GDF-15 Antibody [NBP1-02492] - Staining of human adrenal. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg Anmelden zum Anzeigen 10 bis 13 Tage
$556.31
Details
Human Maus Unkonjugiert FACS, IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen HRP ELISA, WB Western blot using affinity purified anti-NAG-1/GDF15 (C-terminal) antibody shows detection NAG-1 purified from CHO cells as a 14 kDa band corresponding to monomer and a 28 kDa band corresponding to dimerized NAG-1. Samples were electro-phoresed on a 4-20% gradient gel under reducing conditions. Lane 1 shows NAG-1 detection. Lane 2 shows reactivity is blocked when this antibody is pre-incubated with the immunizing peptide prior to Western blotting. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details

GDF15 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GDF15 Antikörper

  1. Human Polyclonal GDF15 Primary Antibody für IHC, IHC (p) - ABIN4313803 : Tabrizi, Kalloger, Köbel, Cipollone, Roskelley, Mehl, Gilks: Primary ovarian mucinous carcinoma of intestinal type: significance of pattern of invasion and immunohistochemical expression profile in a series of 31 cases. in International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 (PubMed)
    Show all 8 Pubmed References

  2. Mouse (Murine) Polyclonal GDF15 Primary Antibody für IHC - ABIN966198 : Iguchi, Chrysovergis, Lee, Baek, Langenbach, Eling: A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2. in Cancer letters 2009 (PubMed)
    Show all 7 Pubmed References

  3. Mouse (Murine) Polyclonal GDF15 Primary Antibody für IHC - ABIN966197 : Cekanova, Lee, Donnell, Sukhthankar, Eling, Fischer, Baek: Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice. in Cancer prevention research (Philadelphia, Pa.) 2009 (PubMed)
    Show all 7 Pubmed References

  4. Mouse (Murine) Polyclonal GDF15 Primary Antibody für IHC - ABIN966196 : Ding, Mracek, Gonzalez-Muniesa, Kos, Wilding, Trayhurn, Bing: Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. in Endocrinology 2009 (PubMed)
    Show all 7 Pubmed References

  5. Human Polyclonal GDF15 Primary Antibody für IF (p), IHC (p) - ABIN704561 : Ruan, Li, Nie, Zhou, Zou: Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal GDF15 Primary Antibody für ELISA, WB - ABIN269826 : Comitato, Nesaretnam, Leoni, Ambra, Canali, Bolli, Marino, Virgili: A novel mechanism of natural vitamin E tocotrienol activity: involvement of ERbeta signal transduction. in American journal of physiology. Endocrinology and metabolism 2009 (PubMed)
    Show all 2 Pubmed References

  7. Mouse (Murine) Polyclonal GDF15 Primary Antibody für ELISA, WB - ABIN1043801 : Baek, Eling: Changes in gene expression contribute to cancer prevention by COX inhibitors. in Progress in lipid research 2006 (PubMed)

Weitere Antikörper gegen GDF15 Interaktionspartner

Human Growth Differentiation Factor 15 (GDF15) Interaktionspartner

  1. we found that GDF-15 -3148C/G polymorphism (CC genotype) might have a correlation with acute ST-elevation myocardial infarction occurrence and the formation of collateral circulation.

  2. Data show that serum growth differentiation factor 15 (GDF15)levels were significantly higher in subjects with thyroid nodules compared with nodule negative subjects, and this was influenced by age.

  3. Findings suggest that GDF15 induces tumor sphere formation through GDF15-ERK1/2-GDF15 circuits, leading to maintenance of GDF15high cancer stem-like cells.

  4. These authors demonstrate that blocking cardiomyocyte production of GDF15 normalizes circulating GDF15 level and restores liver growth hormone (zeige GH1 Antikörper) signaling, establishing GDF15 as a bona fide heart-derived hormone that regulates pediatric body growth.

  5. Authors demonstrated that GDF15 contributed to radioresistance of HNC (zeige MMP8 Antikörper), as determined by both gain- and lost-of-functional experiments. Authors further showed that GDF15 facilitated the conversion of cancer stemness, as assessed by the promotion of CD44 (zeige CD44 Antikörper)+ and ALDH1 (zeige ALDH1A1 Antikörper)+ cell populations and spheroid cell formation.

  6. this study, for the first time, demonstrates that GDF15 is a promising target for preventing cold I/R injury in heart transplantation. This study also shows that the resultant protective effects are mediated by the Foxo3 and NFkappaB signaling pathways

  7. High circulating GDF-15 levels are predictive of secondary cardiovascular events in women but not in men with carotid atherosclerosis.

  8. In patients with chronic obstructive pulmonary disease, high levels of GDF15 were independently associated with a higher yearly rate of exacerbations, higher mortality and increased decline in both FEV1 and FVC.

  9. Data suggested NAG-1 protein as a crucial mediator of epithelial ovarian cancer (EOC) progression and resistance to the standard first-line chemotherapy against EOC, particularly in MyD88 (zeige MYD88 Antikörper)-positive ovarian cancer stem-like cells.

  10. The GDF-15 gene rs1804826G/T polymorphism and sGDF-15 levels are associated with ischemic stroke in the Chinese population.

Mouse (Murine) Growth Differentiation Factor 15 (GDF15) Interaktionspartner

  1. Membrane-protein extraction and use of an intracellular protein (zeige CKAP2 Antikörper)-transport inhibitor showed that GDF-15 promoted CaV3.1 (zeige CACNA1G Antikörper) and CaV3.3 (zeige CACNA1I Antikörper) alpha-subunit (zeige POLG Antikörper) expression by trafficking to the membrane.

  2. CHOP (zeige DDIT3 Antikörper) activates Gdf15 transcription via binding to its promoter upon endoplasmic reticulum stress.

  3. The ANT1 (zeige SLC25A4 Antikörper)-deficient muscle mitochondria produce excess reactive oxygen species (ROS (zeige ROS1 Antikörper)) and are partially uncoupled. Hence, the muscle respiration under nonphosphorylating conditions is increased. Muscle transcriptome analysis revealed the induction of mitochondrial biogenesis, down-regulation of diabetes-related genes, and increased expression of the genes encoding the myokines FGF21 (zeige FGF21 Antikörper) and GDF15.

  4. isolating GFRAL as the receptor for GDF15-induced anorexia and weight loss, the identification of a mechanistic basis for the non-homeostatic regulation of neural circuitry by a peripheral signal associated with tissue damage and stress; findings provide opportunities to develop therapeutic agents for the treatment of disorders with altered energy demand

  5. These data suggest that GDF15 is required for IL-13 (zeige IL13 Antikörper)-induced improvement of glucose intolerance in mice fed an HFD.

  6. HIF-1alpha (zeige HIF1A Antikörper) and GDF15 expression are inversely related under normoxia and hyperoxia.

  7. This is the first study defining the role of Mic-1/Gdf15 in a number of behavioural domains.

  8. epithelial restitution was promoted by enhanced NAG-1 expression and subsequent enterocyte locomotion during the early wound-healing process

  9. both GDF-15 and TGF-beta1 (zeige TGFB1 Antikörper) counteract chemokine (zeige CCL1 Antikörper)-induced integrin activation on neutrophils via the ALK-5 (zeige TGFBR1 Antikörper)/TGF-betaRII heterodimer.

  10. GDF15 is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (zeige INS Antikörper) resistance.

GDF15 Antigen-Profil

Protein Überblick

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Genbezeichner und Symbole assoziert mit GDF15

  • growth differentiation factor 15 (GDF15) Antikörper
  • growth differentiation factor 15 (Gdf15) Antikörper
  • GDF-15 Antikörper
  • GDF15 Antikörper
  • MIC-1 Antikörper
  • MIC1 Antikörper
  • NAG-1 Antikörper
  • PDF Antikörper
  • PLAB Antikörper
  • PTGFB Antikörper
  • SBF Antikörper

Bezeichner auf Proteinebene für GDF15

growth differentiation factor 15 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , GDF-15 , macrophage inhibiting cytokine-1

GENE ID SPEZIES
719466 Macaca mulatta
9518 Homo sapiens
23886 Mus musculus
29455 Rattus norvegicus
468770 Pan troglodytes
100718010 Cavia porcellus
100379630 Sus scrofa
484822 Canis lupus familiaris
618677 Bos taurus
100913168 Ovis aries
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