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GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
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Data suggest in vitro-matured oocytes and 1-cell to 4-cell stage embryos exhibit GLIS1 transcripts; GLIS1 transcripts are absent/at trace levels at 8-cell to blastocyst stages; GLIS1 is important factor for preimplantation development of embryos.
These results suggest that the hypoxic signaling pathway may play a pivotal role in regulating the reprogramming factor GLIS1, via non-canonical mechanisms involving partner transcription factor rather than by direct HIF transactivation.
found that allele 'A' of rs797906 SNP increases the risk for late-onset Parkinson Disease in the Han Chinese population.
results therefore show that Glis1 effectively promotes the direct reprogramming of somatic cells during iPSC generation.
Transcriptional factor Glis1 is involved in the regulation of aberrant differentiation observed in psoriatic epidermis.
Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells into myocytes while preventing brown adipocyte differentiation of satellite cells via repressing expression of the novel pro-adipogenic transcription factor Glis1.
Glis1 may play a critical role in the control of gene expression during specific stages of embryonic development.
GliH1 has homology to the Gli zinc finger domain but is not required for mouse development
GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002
zinc finger protein GLIS1
, GLIS family zinc finger 1
, novel zinc finger protein
, zinc finger protein GLIS1-like
, GLI-similar 1
, GLI-Kruppel family member GLI6
, Glis1 Kruppel-like zinc finger protein
, gli homologous protein 1
, zinc finger transcription factor Gli5