GLIS1 Antikörper (N-Term)

Produktnummer ABIN6971686

Der Ratte Monoklonal anti-GLIS1 Antikörper (Klon 7-14) (ABIN6971686) detektiert spezifisch GLIS1 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für GLIS1 Antikörper (N-Term) (ABIN6971686)

Target: GLIS1 (GLIS Family Zinc Finger 1 (GLIS1))

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser GLIS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: 7-14

Produktdetails anti-GLIS1 Antikörper

Bindungsspezifität: N-Term

Produktmerkmale: GLIS1 (Glis Family Zinc Finger 1) belongs to a GLIS subfamily of Krüppel-like zinc-finger transcription factors characterized to regulate a set of downstream targets essential for cellular functions, including pancreatic development, b-cell maturation and maintenance, and insulin production. GLIS1 is enriched in unfertilized eggs and embryos and it can be used to promote direct reprogramming of somatic cells to induced pluripotent stem cells (iPS cells). GLIS1 may regulate the expression of numerous genes, either positively or negatively, and is implicated in mitral valve development, where dysregulation may lead to mitral valve prolapse (MVP). GLIS1 antibody (mAb) (Clone 7-14) was raised in a Rat host. It has been validated for use in Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

Aufreinigung: Protein G Chromatography

Immunogen: This antibody was raised against a peptide within the amino-terminal half of human GLIS1 (GLI-similar 1), which shares homology with mouse GLIS1.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu GLIS1

Target: GLIS1 (GLIS Family Zinc Finger 1 (GLIS1))

Andere Bezeichnung: GLIS1

Molekulargewicht: 95 kDa

NCBI Accession: NP_671726