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Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity..
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Human Polyclonal CABP7 Primary Antibody für WB - ABIN531146
Mikhaylova, Reddy, Munsch, Landgraf, Suman, Smalla, Gundelfinger, Sharma, Kreutz: Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking. in Proceedings of the National Academy of Sciences of the United States of America 2009
CaBP7 regulates lysosome clustering at the intercellular bridge during cytokinesis in HeLa cells. CaBP7 depletion induces lysosome mislocalization, extension of intercellular bridge lifetime, and cytokinesis failure.
Data indicate that the Ca(2 (zeige CA2 Antikörper)+)-bound form of calcium-binding protein 7 (CaBP7) N-terminal domain (NTD) is monomeric and exhibits an open conformation.
CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca(2 (zeige CA2 Antikörper)+)-sensing by these family members.
Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
calcium binding protein 7
, calcium binding protein 7-like
, calcium-binding protein 7
, calneuron 2
, calneuron II
, calcium-binding protein CaBP7