anti-ArfGAP with Dual PH Domains 1 (ADAP1) Antikörper

binds inositol(1,3,4,5)tetrakisphosphate (InsP4) and phosphatidylinositol(3,4,5)trisphosphate (PtdInsP3)\;involved in inositol phosphate or inositol lipid signal transduction [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen ADAP1 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ADAP1 11033 O75689
ADAP1 231821  
ADAP1 171097  
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Top anti-ADAP1 Antikörper auf antikoerper-online.de

Showing 10 out of 55 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Centa1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Mouse Kidney WB Suggested Anti-Centa1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Mouse Kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185094 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.84
Details
Human Maus Unkonjugiert ELISA, FACS, IHC, WB ELISA: Centaurin alpha 1 Antibody (3E2D9)  - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Flow Cytometry: Centaurin alpha 1 Antibody (3E2D9)  - Analysis of K562 cells using ADAP1 mouse mAb (green) and negative control (red). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$516.98
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric tissue, using Centaurin alpha 1, antibody at 1:100 dilution. WB Image Sample(30 μg of whole cell lysate) A: A431 , B: HeLaS3 7.5% SDS PAGE antibody diluted at 1:500 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
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Huhn Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$610.50
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Western Blot; Sample: Mouse Cerebrum lysate; Primary Ab: 3µg/ml Rabbit Anti-Human CENTa1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$314.00
Details
Hund Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 4 bis 8 Tage
$462.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: Centaurin alpha 1 Antibody [NBP1-31179] - Paraffin-embedded gastric tissue, using antibody at 1:100 dilution. Western Blot: Centaurin alpha 1 Antibody [NBP1-31179] - A: 293T B :H1299 7.5% SDS PAGE; antibody diluted at 1:500 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$516.98
Details
Human Maus Unkonjugiert ELISA, FACS, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using ADAP1 mAb against human ADAP1 (AA: 240-370) recombinant protein. (Expected MW is 41.6 kDa) 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
$430.10
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using ADAP1 antibody. Western blot analysis of extracts of various cell lines, using ADAP1 antibody (ABIN1870810) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. 100 μL Anmelden zum Anzeigen 11 bis 13 Tage
$366.77
Details

Am meisten referenzierte anti-ADAP1 Antikörper

  1. Human Polyclonal ADAP1 Primary Antibody für ELISA, WB - ABIN268683 : Venkateswarlu, Oatey, Tavaré, Jackson, Cullen et al.: Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) ... in The Biochemical journal 1999 (PubMed)

Weitere Antikörper gegen ADAP1 Interaktionspartner

Human ArfGAP with Dual PH Domains 1 (ADAP1) Interaktionspartner

  1. Analyzed ArfGAP with dual PH domains 1 (ADAP1) using mass spectrometry and found that ADAP1 is phosphorylated at Y364.

  2. This review highlights the functions of the neuron-specific protein ADAP1 in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1. [review]

  3. SH-SY5Y cells, stably transfected with GFP-tagged-p42(IP4), show an enhanced NRD protein expression already at an earlier time point after retinoic acid stimulation.

  4. Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-alpha1 (ADAP1).

  5. Full-length KIF13B and CENTA1 form heterotetramers that can bind four phosphoinositide molecules in the vesicle and transport it along the microtubule.

  6. The ARFGAP domain of p42IP4 is involved in the interaction and co-localization with RanBPM protein, without being the only interaction site.

  7. the up-regulated p42(IP4) in Alzheimer's disease neurons may serve as a docking protein to recruit signaling molecules such as different subtypes of casein kinase I to the plasma membrane.

  8. Results show that nucleolin interacts with centaurin-alpha(1) protein, suggesting that centaurin-alpha(1) may be part of a ribonucleoprotein complex.

  9. centaurin-alpha1 negatively regulates ARF6 activity by functioning as an in vivo PIP3-dependent ARF6 GAP

  10. p42IP4 receptor is expressed and distributed throughout the cell in HEK cell lines and is located on chromosome 7, position 7p22.3.

  11. Authors propose alternative concepts of how elevated levels of p42IP4 might relate to its interaction with nucleolin in the pathomechanisms of Alzheimer's disease.

  12. The centaurin, alpha 1 protein is a high-affinity PtdIns(3,4,5)P3-binding protein enriched in brain. Sequence analysis indicates centaurin alpha-1 contains two pleckstrin homology domains, ankyrin repeats and an Arf GAP homology domain.

  13. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2-adrenoceptor internalization.

  14. Centaurin-alpha1 contributes to ERK activation in growth factor signaling, linking the PI3K pathway to the ERK mitogen-activated protein kinase pathway.

  15. Data show that membrane transport of p42(IP4) induced by epidermal growth factor is inhibited by stimulation of phospholipase C-coupled thrombin receptor.

  16. p42IP4 binds to nardilysin via the acidic domain, and that this interaction is controlled by the cognate cellular ligands of p42IP4/centaurin-alpha1

ADAP1 Antigen-Profil

Protein Überblick

binds inositol(1,3,4,5)tetrakisphosphate (InsP4) and phosphatidylinositol(3,4,5)trisphosphate (PtdInsP3)\;involved in inositol phosphate or inositol lipid signal transduction

Genbezeichner und Symbole assoziert mit ADAP1

  • ArfGAP with dual PH domains 1 (ADAP1) Antikörper
  • ArfGAP with dual PH domains 1 (adap1) Antikörper
  • ArfGAP with dual PH domains 1 L homeolog (adap1.L) Antikörper
  • ArfGAP with dual PH domains 1 (Adap1) Antikörper
  • 4930431P11Rik Antikörper
  • Centa1 Antikörper
  • centa2 Antikörper
  • GC1L Antikörper
  • GCS1L Antikörper
  • MGC76109 Antikörper
  • p42IP4 Antikörper

Bezeichner auf Proteinebene für ADAP1

centaurin, alpha 1 , ArfGAP with dual PH domains 1 , Centaurin-alpha2 protein , arf-GAP with dual PH domain-containing protein 1-like , arf-GAP with dual PH domain-containing protein 1 , inositol(1,3,4,5)tetrakisphosphate receptor , centaurin-alpha , centaurin-alpha-1 , cnt-a1 , putative MAPK-activating protein PM25

GENE ID SPEZIES
416451 Gallus gallus
394901 Xenopus (Silurana) tropicalis
495044 Xenopus laevis
696246 Macaca mulatta
750938 Pan troglodytes
100410764 Callithrix jacchus
100472030 Ailuropoda melanoleuca
100558369 Anolis carolinensis
397453 Sus scrofa
11033 Homo sapiens
231821 Mus musculus
606942 Canis lupus familiaris
171097 Rattus norvegicus
282176 Bos taurus
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