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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Zusätzlich bieten wir Ihnen ATG4 Autophagy Related 4 Homolog A (S. Cerevisiae) Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal ATG4A Primary Antibody für IHC (p), WB - ABIN1882158
Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005
Show all 6 Pubmed References
Human Polyclonal ATG4A Primary Antibody für ELISA, IHC - ABIN4282098
Scherz-Shouval, Sagiv, Shorer, Elazar: The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A. in The Journal of biological chemistry 2003
Cow (Bovine) Polyclonal ATG4A Primary Antibody für WB - ABIN2775554
Bortnik, Choutka, Horlings, Leung, Baker, Lebovitz, Dragowska, Go, Bally, Minchinton, Gelmon, Gorski: Identification of breast cancer cell subtypes sensitive to ATG4B inhibition. in Oncotarget 2016
An intron SNP rs807185 in ATG4A might be a protective factor for lung cancer.
ATG4A promotes the metastasis of gastric cancer cells via the Notch (zeige NOTCH1 Antikörper) signaling pathway, which is an autophagy-independent mechanism
The structure and regulatory machinery of Atg4a [review]
We conclude that miR (zeige MLXIP Antikörper)-24-3p regulates autophagy by targeting ATG4A
The autophagy regulator ATG4A was found to be essential for the maintenance of a sub-population with cancer stem cell properties and to regulate breast cancer cell tumourigenicity.
The demonstration that expression of ATG4A in cells increased stem properties provided an indication of its biological function. Hypomethylation of ATG4A and HIST1H2BN in ovarian tumor-initiating cells predicts poor prognosis for ovarian cancer patients.
The actions of ATG4 family members (particularly ATG4B (zeige ATG4B Antikörper)) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts.
statistical analysis of APG4A gene confirmed the characterisation of each protein-coding gene present in human genome Xq22.1
Atg4B (zeige ATG4B Antikörper) possessed the broadest spectrum against all substrates, followed by Atg4A for ATG8 (zeige GABARAPL2 Antikörper) substrates
HsApg4A cleaves the COOH terminus of GATE-16 (zeige GABARAPL2 Antikörper)
MiR (zeige MLXIP Antikörper)-144 inhibits the autophagy-related gene Atg4a expression in Mycobacterium tuberculosis infection.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
ATG4 autophagy related 4 homolog A
, autophagy-related protein 4 homolog A
, cysteine protease ATG4A
, autophagy-related cysteine endopeptidase 2
, Cysteine protease ATG4A
, autophagy-related cysteine endopeptidase 2A
, APG4 autophagy 4 homolog A
, AUT-like 2 cysteine endopeptidase
, AUT-like 2, cysteine endopeptidase
, autophagin 2
, APG4 (ATG4) autophagy-related homolog A
, autophagy 4 homolog A
, autophagy-related 4A
, cysteine protease APG4A
, autophagy related 4 homolog A
, autophagy related 4A, cysteine peptidase
, uncharacterized protein LOC678769