anti-Human FZD7 Antikörper für Immunohistochemistry

Recommended FZD7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Frizzled Family Receptor 7 (FZD7) Antikörper
  • Fz-7
  • Xfz7
  • frizzled-7
  • frizzled7
  • frz-7
  • frz7
  • fz7
  • fze3
  • FzE3
  • fzd7-a
  • fzd7-b
  • cFz-7
  • Fz7
  • frizzled family receptor 7
  • frizzled homolog 7 (Drosophila)
  • frizzled-7-like
  • FZD7
  • fzd7
  • Fzd7
  • LOC100513691
Epitop
C-Term
33
27
15
14
14
10
8
4
3
3
2
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Yeast
152
108
30
9
9
9
7
7
6
3
2
1
1
Wirt
Kaninchen
89
52
25
11
2
Klonalität
Polyklonal
Konjugat
Dieser FZD7 Antikörper ist unkonjugiert
11
5
5
5
5
4
4
4
4
4
4
4
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
98
68
37
28
18
14
10
7
6
2
1
Optionen
Hersteller
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Produktnummer ABIN2776708
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
8.868737 ABIN2469409 IHC ELISA Rabbit C-Term Anmelden zum Anzeigen Polyclonal
8.868737 ABIN635842 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN4312613 IHC IHC (p) Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2462375 IHC ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN393087 FACS IHC ELISA Biotin Rat IgG2a Cysteine-Rich Domain, Extracellular Anmelden zum Anzeigen
1 ABIN2269691 IHC Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2269701 IHC ELISA WB Goat C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2269702 IHC Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2269693 IHC Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2269711 IHC Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2270567 IHC ELISA WB Mouse IgG1 kappa AA 155-254 Anmelden zum Anzeigen 4D9
1 ABIN2771308 IHC (p) IHC ELISA WB Goat C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2765212 IHC (p) IHC ELISA Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN643474 IF (p) IHC Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Frizzled Family Receptor 7 (FZD7) Antikörper
Epitop C-Term
(33), (27), (15), (14), (14), (10), (8), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Yeast
(152), (108), (30), (9), (9), (9), (7), (7), (6), (3), (2), (1), (1)
Wirt Kaninchen
(89), (52), (25), (11), (2)
Klonalität
Polyklonal
Konjugat Dieser FZD7 Antikörper ist unkonjugiert
(11), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(98), (68), (37), (28), (18), (14), (10), (7), (6), (2), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FZD7 Antikörper

Target Details FZD7 Anwendungsinformationen Handhabung Referenzen für anti-FZD7 Antikörper (ABIN2776708) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977173.
Sequenz PDFTVFMIKY LMTMIVGITT GFWIWSGKTL QSWRRFYHRL SHSSKGETAV
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%
Produktmerkmale This is a rabbit polyclonal antibody against FZD7. It was validated on Western Blot and immunohistochemistry.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human FZD7

Target Details FZD7

Produktdetails anti-FZD7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-FZD7 Antikörper (ABIN2776708) Bilder zurück nach oben
Antigen
Andere Bezeichnung FZD7 (FZD7 Antibody Abstract)
Hintergrund FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Alias Symbols: FzE3
Protein Interaction Partner: UBC, UBQLN4, MAGI3, UBQLN1, DLG2, DLG4, DLG1,
Protein Size: 574
Molekulargewicht 63 kDa
Gen-ID 8324
NCBI Accession NM_003507, NP_003498
UniProt O75084
Pathways WNT Signalweg, Stem Cell Maintenance

Anwendungsinformationen

Produktdetails anti-FZD7 Antikörper Target Details FZD7 Handhabung Referenzen für anti-FZD7 Antikörper (ABIN2776708) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 574 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FZD7 Antikörper Target Details FZD7 Anwendungsinformationen Referenzen für anti-FZD7 Antikörper (ABIN2776708) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FZD7 Antikörper (ABIN2776708)

Produktdetails anti-FZD7 Antikörper Target Details FZD7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

McIver, Stanger, Santarelli, Roman, Nixon, McLaughlin: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, 2012

Schmuck, Warneke, Behrens, Simon, Weichert, Röcken: "Genotypic and phenotypic characterization of side population of gastric cancer cell lines." in: The American journal of pathology, Vol. 178, Issue 4, pp. 1792-804, 2011

Gökmen-Polar, Toroni, Hocevar, Badve, Zhao, Shen, Bruckheimer, Kinch, Miller: "Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer." in: Breast cancer research and treatment, Vol. 127, Issue 2, pp. 375-84, 2011

Ohba, Lanigan, Roessler: "Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 18, Issue 12, pp. 1620-9, 2010

Ueno, Hiura, Suehiro, Hazama, Hirata, Oka, Imai, Dahiya, Hinoda: "Frizzled-7 as a potential therapeutic target in colorectal cancer." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 7, pp. 697-705, 2008

Allgemeine Veröffentlichungen

Vincan, Darcy, Smyth, Thompson, Thomas, Phillips, Ramsay: "Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth." in: Differentiation; research in biological diversity, Vol. 73, Issue 4, pp. 142-53, 2005

Bilder

Produktdetails anti-FZD7 Antikörper Target Details FZD7 Anwendungsinformationen Handhabung Referenzen für anti-FZD7 Antikörper (ABIN2776708) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) WB Suggested Anti-FZD7 Antibody Titration: 0.2-1 ug/ml
Positive Control:...
Immunohistochemistry (IHC) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) WB Suggested Anti-FZD7
Antibody Titration: 0.2-1 µg/mL
Positive Control...