FZD7 Antikörper (AA 45-94)
Kurzübersicht für FZD7 Antikörper (AA 45-94) (ABIN1535614)
Target
Alle FZD7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 45-94
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Verwendungszweck
- Frizzled-7 Antibody
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Spezifität
- Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,Flow Cyt 1:50-200,IF ICC 1:100-500,ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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Andere Bezeichnung
- FZD7
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Hintergrund
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Synonyms: FZD7; Frizzled-7; Fz-7; hFz7; FzE3
Background: frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],
Gene Name: FZD7
Protein Name: Frizzled-7
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Molekulargewicht
- 63 kDa
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Gen-ID
- 8324
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OMIM
- 603410
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UniProt
- O75084
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Pathways
- WNT Signalweg, Stem Cell Maintenance
Target
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