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NFKBIA Antikörper (AA 12-41)

NFKBIA Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21911 unconjugated
Produktnummer ABIN652417
  • Target Alle NFKBIA Antikörper anzeigen
    NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
    Bindungsspezifität
    • 53
    • 28
    • 24
    • 21
    • 18
    • 16
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-41
    Reaktivität
    • 253
    • 166
    • 133
    • 28
    • 19
    • 17
    • 14
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 217
    • 24
    • 7
    • 5
    Kaninchen
    Klonalität
    • 204
    • 48
    Polyklonal
    Konjugat
    • 111
    • 21
    • 13
    • 12
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    Dieser NFKBIA Antikörper ist unkonjugiert
    Applikation
    • 176
    • 105
    • 67
    • 66
    • 50
    • 38
    • 32
    • 31
    • 22
    • 16
    • 14
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    M, Pig
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NFKBIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-41 amino acids from human NFKBIA.
    Klon
    RB21911
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NFKBIA Primärantikörper
  • Applikationshinweise
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
    Andere Bezeichnung
    NFKBIA (NFKBIA Produkte)
    Synonyme
    IKBA antikoerper, MAD-3 antikoerper, NFKBI antikoerper, AI462015 antikoerper, Nfkbi antikoerper, RL/IF-1 antikoerper, ECI-6/IKBA antikoerper, NFKBIA antikoerper, ikbaB antikoerper, wu:fb81f08 antikoerper, zgc:56666 antikoerper, zgc:77616 antikoerper, ikbaA antikoerper, wu:fj16a07 antikoerper, zgc:85769 antikoerper, NFKB inhibitor alpha antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a antikoerper, NFKBIA antikoerper, Nfkbia antikoerper, nfkbiab antikoerper, nfkbiaa antikoerper
    Hintergrund
    NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).
    Molekulargewicht
    35609
    Gen-ID
    4792
    NCBI Accession
    NP_065390
    UniProt
    P25963
    Pathways
    NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling
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