anti-PARG (PARG) Antikörper

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. Zusätzlich bieten wir Ihnen PARG Proteine (5) und PARG Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PARG 8505 Q86W56
PARG 26430  
PARG 83507 Q9QYM2
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-PARG Antikörper auf antikoerper-online.de

Showing 10 out of 41 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PARG AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Jurkat Whole Cell 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of Parg Antibody (C-term) in 293 cell line lysates (35 µg/lane). Parg (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of Parg (arrow) using rabbit polyclonal Parg Antibody (C-term) (ABIN391439).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the Parg gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PARG Antibody (C-term) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the PARG antibody detected the PARG protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
340,48 €
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using PARG antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Kaninchen Unkonjugiert WB PARG Antibody (C-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PARG antibody detected the PARG protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of PARG expression in transfected 293T cell line by PARG MaxPab polyclonal antibody.<br><br>Lane 1: PARG transfected lysate(107.36 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to PARG on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemistry: PARG Antibody (6F4) [NBP2-46320] - Analysis of Adenocarcinoma of Human breast tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) Immunohistochemistry: PARG Antibody (6F4) [NBP2-46320] - Analysis of Adenocarcinoma of Human endometrium tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: PARG Antibody  - Staining of human cell line MCF7 shows localization to nucleoplasm. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details

PARG Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
,
,
, , , , ,
Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-PARG Antikörper

  1. Human Polyclonal PARG Primary Antibody für IF, WB - ABIN521952 : Boudra, Bolin, Chiker, Fouquin, Zaremba, Vaslin, Biard, Cordelières, Mégnin-Chanet, Favaudon, Fernet, Pennaneach, Hall: PARP-2 depletion results in lower radiation cell survival but cell line-specific differences in poly(ADP-ribose) levels. in Cellular and molecular life sciences : CMLS 2015 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PARG Interaktionspartner

Human PARG Interaktionspartner

  1. PARG is acetylated at multiple sites.PARG interacts with PCNA (zeige PCNA Antikörper) via a non-canonical PIP (zeige PIP Antikörper)-box.

  2. PARG inhibition leads to stalled replication forks and increased homologous recombination (HRR). The lack of HRR proteins at PARG inhibitor-induced replication stalling that induces cell death.

  3. Data show that poly-(ADP-ribose) polymerase 1 (PARP1 (zeige PARP1 Antikörper)) opposes the function of poly-(ADP-ribose) glycohydrolase (PARG) during regulation of bone morphogenetic protein target gene expression.

  4. Poly(ADP-ribosyl) glycohydrolase (PARG) is involved in cell proliferation and DNA synthesis, with depletion leading to replication-coupled H2AX (zeige H2AFX Antikörper) phosphorylation. In addition, PARG depletion or inhibition slows down individual replication forks similarly to mild chemotherapeutic treatment.

  5. Studies indicate that poly (ADP-ribose) glycohydrolase (PARG) and terminal ADP-ribose glycohydrolase 1 (TARG1 (zeige NDRG1 Antikörper)) are key enzymes in poly(ADP-ribose) polymerases (PARPs)-mediated ADP-ribosylation.

  6. Nuclear Smad (zeige SMAD1 Antikörper) function is negatively regulated by PARP-1 (zeige PARP1 Antikörper) that is assisted by PARP-2 (zeige PARP2 Antikörper) and positively regulated by PARG during the course of TGFB (zeige TGFB1 Antikörper) signaling.

  7. Radiation-induced G2/M arrest was largely suppressed by PARG siRNA in PC-14 and A427 cells, which exhibited significantly enhanced radiosensitivity in response to PARG knockdown.

  8. The amount of poly(ADP-ribose) in a cell is regulated under the control of PARP1 (zeige PARP1 Antikörper)/PARG gene expression balance.

  9. PARG knockdown enhances sensitivity to MMS in MIAPaCa2 and RKO tumor cell lines.

  10. poly(ADP-ribose) glycohydrolase is crucial for Trypanosoma cruzi infection cycle.

Mouse (Murine) PARG Interaktionspartner

  1. This study contributes to the understanding of PARG catalytic and regulatory mechanisms as well as the rational design of PARG inhibitors.

  2. PARG110 knockout retinal explants were highly resistant to cyclic GMP (zeige NT5C2 Antikörper) toxicity.

  3. we investigated the role of PARG in photoreceptor degeneration using the PARG-110 knock out mouse and report for the first time on PARG expression in wild-type and knock-out retina.

  4. PARG release of PAR (zeige AFG3L2 Antikörper) attached to nuclear proteins, followed by ARH3 (zeige ADPRHL2 Antikörper) cleavage of PAR (zeige AFG3L2 Antikörper), is essential in regulating PAR (zeige AFG3L2 Antikörper)-dependent apoptosis-inducing factor (zeige AIFM1 Antikörper) release from mitochondria and parthanatos.

  5. Data indicate that poly(ADP-ribose) glycohydrolase Parg(-/-) cells were more sensitive to gamma-irradiation than poly(ADP-ribose) polymerase-1 Parp-1 (zeige PARP1 Antikörper)(-/-) cells.

  6. Results define PARG as a coactivator regulating chromatin remodeling during retinoic acid receptor (zeige RARA Antikörper)-dependent gene expression.

  7. Results demonstrate nuclear AIF (zeige AIFM1 Antikörper) translocation only in PARG-null TS cells, which demonstrates the presence of AIF (zeige AIFM1 Antikörper)-mediated cell death.

  8. PARP-1 (zeige PARP1 Antikörper)/PARG control a cell death signal pathway that operates between five different cell compartments and communicates via three types of chemical messengers: a nucleotide, a cation, and proteins

  9. PARG-deficient cells showed a compromised DNA repair and increased genomic instability.

  10. Hydrolysis of PARP (zeige PARP1 Antikörper) requires PARG.

PARG Antigen-Profil

Protein Überblick

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products.

Genbezeichner und Symbole assoziert mit anti-PARG (PARG) Antikörper

  • poly (ADP-ribose) glycohydrolase (PARG) Antikörper
  • poly (ADP-ribose) glycohydrolase (Parg) Antikörper
  • AI413217 Antikörper
  • PARG99 Antikörper

Bezeichner auf Proteinebene für anti-PARG (PARG) Antikörper

mitochondrial poly(ADP-ribose) glycohydrolase , poly(ADP-ribose) glycohydrolase , poly(ADP-ribose) glycohydrolase 60 kDa isoform , cytosolic poly(ADP-ribose) glycohydrolase , mitochondrial poly(ADP-ribose) glycohydrolase 63 kDa isoform

GENE ID SPEZIES
8505 Homo sapiens
26430 Mus musculus
83507 Rattus norvegicus
281377 Bos taurus
Ausgewählte Anbieter für anti-PARG (PARG) Antikörper
Haben Sie etwas anderes gesucht?