Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PARG Antikörper (AA 1-348) (FITC)

PARG Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7163767
  • Target Alle PARG Antikörper anzeigen
    PARG
    Bindungsspezifität
    • 10
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-348
    Reaktivität
    • 35
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 30
    • 5
    Kaninchen
    Klonalität
    • 32
    • 3
    Polyklonal
    Konjugat
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    Dieser PARG Antikörper ist konjugiert mit FITC
    Applikation
    Bitte anfragen
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Poly(ADP-ribose) glycohydrolase protein (1-348AA)
    Isotyp
    IgG
    Top Product
    Discover our top product PARG Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PARG
    Andere Bezeichnung
    PARG (PARG Produkte)
    Synonyme
    PARG99 antikoerper, AI413217 antikoerper, poly(ADP-ribose) glycohydrolase antikoerper, poly (ADP-ribose) glycohydrolase antikoerper, PARG antikoerper, Parg antikoerper
    Hintergrund

    Background: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP-ribose monomers (PubMed:23102699). Required for retinoid acid-dependent gene transactivation, probably by dePARsylating histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters (PubMed:23102699). Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257).

    Aliases: ADP riboseglycohydrolase antibody, Mitochondrial poly(ADP ribose) glycohydrolase antibody, Parg antibody, PARG_HUMAN antibody, PARG99 antibody, Poly antibody, poly (ADP ribose) glycohydrolase antibody, poly(ADP-ribose) glycohydrolase 60 kDa isoform antibody, Poly(ADP-ribose) glycohydrolase antibody

    UniProt
    Q86W56
Sie sind hier:
Kundenservice