TNK2 Produkte
(tyrosine Kinase, Non-Receptor, 2 (TNK2))
Kategorien
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte TNK2 Kategorien
TNK2 Antikörper
High quality antibodies with extensive validation data.
TNK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TNK2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TNK2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (4)
Kat. Nr.
ABIN392082
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP
Validierungen
- (4)
Kat. Nr.
ABIN523561
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN683323
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TNK2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971025
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960331
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4885963
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TNK2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7551802
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7562457
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323266
Menge
25 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TNK2 Produkten
: "Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded." in: Cell discovery, Vol. 2, pp. 15047, (2016) (PubMed).: "ACK1 promotes hepatocellular carcinoma progression via downregulating WWOX and activating AKT signaling." in: International journal of oncology, Vol. 46, Issue 5, pp. 2057-66, (2015) (PubMed).
: "Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck." in: The Journal of biological chemistry, Vol. 278, Issue 48, pp. 47713-23, (2003) (PubMed).
Synonyme und alternative Namen zu TNK2
tyrosine kinase non receptor 2 (TNK2), tyrosine kinase, non-receptor, 2 (Tnk2), tyrosine kinase non receptor 2 (Tnk2), tyrosine kinase, non-receptor, 1 (tnk1), ACK, Ack, ACK-1, ACK1, ack1, ackb, AW552477, Cdgip, p21cdc42Hs, Pyk1, tnk2, tnk2b, wu:fj16g04, zgc:154019Bezeichner auf Proteinebene für TNK2
- activated CDC42 kinase 1
- activated Cdc42-associated kinase 1
- activated p21cdc42Hs kinase
- tyrosine kinase non-receptor protein 2
- ACK-1
- Cdc42 GTPase-inhibiting protein
- P21cdc42Hs kinase
- non-receptor protein tyrosine kinase ACK
- activated CDC42 kinase 2
- tyrosine kinase, non-receptor, 2
- tyrosine kinase, non-receptor, 2b
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