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Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine

(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. [provided by RefSeq, Jul 2008].
RANKL Protein (AA 63-244) (His-DYKDDDDK Tag) RANKL Protein (AA 63-244) (His-DYKDDDDK Tag) RANKL Protein (AA 63-244) (His-DYKDDDDK Tag) (ABIN7275517)

TNFSF11 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE

RANKL Protein (AA 63-244) RANKL Protein (AA 63-244) RANKL Protein (AA 63-244) (ABIN7275516)

TNFSF11 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

RANKL Protein (AA 70-316) (His tag) RANKL Protein (AA 70-316) (His tag) RANKL Protein (AA 70-316) (His tag) (ABIN7275518)

TNFSF11 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine nach Origin

Hier sind Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine für eine Vielzahl von Species wie anti-Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11, anti-Mouse Tumor Necrosis Factor (Ligand) Superfamily, Member 11, anti-Rat Tumor Necrosis Factor (Ligand) Superfamily, Member 11 zu finden. Die unten aufgeführten Species gehören zu den verfügbaren Arten. Klicken Sie auf einen Link, um zu den entsprechenden Produkten zu gelangen.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine nach Source

Hier finden Sie Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine Proteine, die nach mehreren wichtigen Quellen organisiert sind. Durch Anklicken eines Links können Sie auf die Produkte zugreifen. Für zusätzliche Quellen nutzen Sie bitte unsere Suchfunktion.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine nach Protein-Typ

Hier können Sie Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine Proteine finden, die nach verfügbaren Proteintypen kategorisiert sind. Zusätzliche Proteintypen können mit unserer Suchfunktion gefunden werden.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine nach Anwendung

Hier sind Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine zu finden, welche für eine bestimmte Anwendung wie WB, SDS, ELISA, Imm validiert wurde. Einige der verfügbaren Anwendungen sind unten aufgeführt. Klicken Sie auf einen Link, um zu den entsprechenden Produkten zu gelangen.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine nach Biologische Aktivität

Hier sind Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine mit einem spezifischen Biologische Aktivität zu finden. Die hier aufgeführten Biologische Aktivität sind einige der verfügbaren. Ein Klick auf den entsprechenden Link führt zu den Produkten.

Häufig verwendete Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275517
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275516
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275518
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana benthamiana)
Validierungen
  • (2)
Kat. Nr. ABIN1019704
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN1112027
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293T Cells
Validierungen
  • (2)
Kat. Nr. ABIN1323211
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7013608
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN6253590
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN5674645
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN6386415
Menge 200 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN6973285
Menge 200 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN1344301
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125527
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323214
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323212
Menge 10 μg
Datenblatt Datenblatt

Aktuelle Publikationen für unsere Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine

Nguyen, Nohe: "Factors that Affect the Osteoclastogenesis of RAW264.7 Cells." in: Journal of biochemistry and analytical studies, Vol. 2, Issue 1, (2017) (PubMed).

Beleut, Rajaram, Caikovski, Ayyanan, Germano, Choi, Schneider, Brisken: "Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 7, pp. 2989-94, (2010) (PubMed).

DAmelio, Isaia, Isaia: "The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease." in: Journal of endocrinological investigation, Vol. 32, Issue 4 Suppl, pp. 6-9, (2009) (PubMed).

Takahashi, Udagawa, Suda: "A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function." in: Biochemical and biophysical research communications, Vol. 256, Issue 3, pp. 449-55, (1999) (PubMed).

Suda, Takahashi, Udagawa, Jimi, Gillespie, Martin: "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families." in: Endocrine reviews, Vol. 20, Issue 3, pp. 345-57, (1999) (PubMed).

Yasuda, Shima, Nakagawa, Yamaguchi, Kinosaki, Mochizuki, Tomoyasu, Yano, Goto, Murakami, Tsuda, Morinaga, Higashio, Udagawa, Takahashi, Suda: "Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 7, pp. 3597-602, (1998) (PubMed).

Wong, Rho, Arron, Robinson, Orlinick, Chao, Kalachikov, Cayani, Bartlett, Frankel, Lee, Choi: "TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells." in: The Journal of biological chemistry, Vol. 272, Issue 40, pp. 25190-4, (1997) (PubMed).

Anderson, Maraskovsky, Billingsley, Dougall, Tometsko, Roux, Teepe, DuBose, Cosman, Galibert: "A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function." in: Nature, Vol. 390, Issue 6656, pp. 175-9, (1997) (PubMed).

Aliase für Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine

TNF superfamily member 11 (TNFSF11) Proteine
tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) Proteine
TNF superfamily member 11 (Tnfsf11) Proteine
TNF receptor superfamily member 11b (TNFRSF11B) Proteine
TNF superfamily member 11 L homeolog (tnfsf11.L) Proteine
CD254 Proteine
cd254 Proteine
hRANKL2 Proteine
Ly109l Proteine
ODF Proteine
odf Proteine
OPG Proteine
OPGL Proteine
opgl Proteine
OPTB2 Proteine
optb2 Proteine
RANKL Proteine
rankl Proteine
sOdf Proteine
sodf Proteine
TNFSF11 Proteine
tnfsf11 Proteine
TRANCE Proteine
Trance Proteine
trance Proteine
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