anti-Ratte (Rattus) TLR4 Antikörper für Immunofluorescence (Cultured Cells)

Recommended TLR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 4 (TLR4) Antikörper
  • ARMD10
  • CD284
  • TLR-4
  • TOLL
  • Lps
  • Ly87
  • Ran/M1
  • Rasl2-8
  • toll like receptor 4
  • toll-like receptor 4
  • TLR4
  • Tlr4
Epitop
AA 780-830
59
30
28
25
16
15
15
15
14
13
11
9
8
8
7
6
5
5
5
5
5
5
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Human, Maus, Ratte (Rattus)
556
274
173
94
72
72
64
26
12
9
4
2
1
1
Wirt
Kaninchen
339
273
47
8
Klonalität
Polyklonal
Konjugat
Dieser TLR4 Antikörper ist unkonjugiert
49
47
47
23
15
14
13
10
9
9
8
6
6
6
6
6
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
394
341
187
136
130
124
98
92
34
32
26
26
25
21
20
16
14
8
7
4
4
3
2
1
1
1
Optionen
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Produktnummer ABIN736491
$ 318.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
21.329033 ABIN5011663 IF (cc) Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0
5.5 ABIN917904 IF (cc) IF (p) Alexa Fluor 488 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 1
1 ABIN917902 IF (cc) IF (p) Alexa Fluor 647 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN917903 IF (cc) IF (p) Alexa Fluor 350 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN917905 IF (cc) IF (p) Alexa Fluor 555 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN736495 IF (cc) IF (p) Cy5 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN736496 IF (cc) IF (p) Cy5.5 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN736497 IF (cc) IF (p) Cy7 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN736494 IF (cc) IF (p) Cy3 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN736498 IF (cc) IF (p) FITC Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2809068 IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011661 IF (cc) IF (p) Alexa Fluor 680 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011662 IF (cc) IF (p) Alexa Fluor 750 Rabbit IgG AA 780-830 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011665 IF (cc) Alexa Fluor 488 Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011666 IF (cc) Alexa Fluor 555 Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011667 IF (cc) Alexa Fluor 594 Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011668 IF (cc) Alexa Fluor 647 Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011670 IF (cc) Alexa Fluor 750 Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011669 IF (cc) Alexa Fluor 680 Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5011671 IF (cc) Cy3 Rabbit IgG AA 715-750 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 4 (TLR4) Antikörper
Epitop AA 780-830
(59), (30), (28), (25), (16), (15), (15), (15), (14), (13), (11), (9), (8), (8), (7), (6), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Human, Maus, Ratte (Rattus)
(556), (274), (173), (94), (72), (72), (64), (26), (12), (9), (4), (2), (1), (1)
Wirt Kaninchen
(339), (273), (47), (8)
Klonalität
Polyklonal
Konjugat Dieser TLR4 Antikörper ist unkonjugiert
(49), (47), (47), (23), (15), (14), (13), (10), (9), (9), (8), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(394), (341), (187), (136), (130), (124), (98), (92), (34), (32), (26), (26), (25), (21), (20), (16), (14), (8), (7), (4), (4), (3), (2), (1), (1), (1)
Pubmed 12 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR4 Antikörper

Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN736491) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from rat TLR4
Isotyp IgG
Plasmids, Primers & others

Target Details TLR4

Produktdetails anti-TLR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN736491) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR4 (TLR4 Antibody Abstract)
Hintergrund

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Subcellular location: Cytoplasm

Synonyms: Lps, Ly87, Ran/M1, Rasl2-8, Toll-like receptor 4, CD284, Tlr4

Gen-ID 21898
UniProt Q9QUK6
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Handhabung Referenzen für anti-TLR4 Antikörper (ABIN736491) Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Referenzen für anti-TLR4 Antikörper (ABIN736491) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen für anti-TLR4 Antikörper (ABIN736491)

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Kulhankova, Kinney, Stach, Gourronc, Grumbach, Klingelhutz, Salgado-Pabón: "The Superantigen Toxic Shock Syndrome Toxin-1 Alters Human Aortic Endothelial Cell Function." in: Infection and immunity, 2018 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Harasymowicz, Clement, Azfer, Burnett, Salter, Simpson: "Regional Differences Between Perisynovial and Infrapatellar Adipose Tissue Depots and Their Response to Class II and Class III Obesity in Patients With Osteoarthritis." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 69, Issue 7, pp. 1396-1406, 2017 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human). Weitere Details: Sample: adipose

Xu, Zheng, Liu, Li, Yang, Shang: "Glaucocalyxin B Alleviates Lipopolysaccharide-Induced Parkinson's Disease by Inhibiting TLR/NF-κB and Activating Nrf2/HO-1 Pathway." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 6, pp. 2091-2104, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: brain

Arfian, Muflikhah, Soeyono, Sari, Tranggono, Anggorowati, Romi: "Vitamin D Attenuates Kidney Fibrosis via Reducing Fibroblast Expansion, Inflammation, and Epithelial Cell Apoptosis." in: The Kobe journal of medical sciences, Vol. 62, Issue 2, pp. E38-44, 2016 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: kidney

Kawakita, Fujimoto, Liu, Nakano, Nakatsuka, Suzuki: "Effects of Toll-Like Receptor 4 Antagonists Against Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage in Mice." in: Molecular neurobiology, 2016 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)). Weitere Details: Sample: brain

Wang, Shi, Lv, Xu, Li, Ge, Xiao, Geng, Liu: "Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-?B Activation in Microglial Cells." in: Inflammation, 2015 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Namisaki, Noguchi, Moriya, Kitade, Aihara, Douhara, Nishimura, Takeda, Okura, Kawaratani, Takaya, Seki, Yoshiji: "Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis." in: Journal of gastroenterology, 2015 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: Intestine

Yang, Wang, Zhang, Yang, Lu, Zhang, Li, Zhang, Li: "Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-?B signaling pathway in isoproterenol-induced myocardial hypertrophy." in: Journal of ethnopharmacology, Vol. 150, Issue 3, pp. 1062-70, 2014 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: left ventricle and neonatal cardiomyocytes

Chen, Yu, Fan, Bian, Ma, Lu, Jin: "Sargassum fusiforme polysaccharide activates nuclear factor kappa-B (NF-?B) and induces cytokine production via Toll-like receptors." in: Carbohydrate polymers, Vol. 105, pp. 113-20, 2014 (Probematerial (Species): Rat (Rattus)).

Xing, Zheng, Zhang, Wang, Xing: "Relationship between toll-like receptor 4 levels in aorta and severity of atherosclerosis." in: The Journal of international medical research, Vol. 42, Issue 4, pp. 958-965, 2014 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human). Weitere Details: Sample: Kidney

Takanashi, Tomosada, Villena, Murata, Takahashi, Chiba, Tohno, Shimazu, Aso, Suda, Ikegami, Itoh, Kawai, Saito, Alvarez, Kitazawa: "Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia coli-mediated inflammation." in: BMC microbiology, Vol. 13, pp. 54, 2013

Tang, Zhou, Wang, Zhang, Wang, Li, Huang: "Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts." in: Archives of oral biology, Vol. 56, Issue 10, pp. 1064-72, 2011 (Probematerial (Species): Human).

Bilder

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN736491) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Formalin-fixed and paraffin embedded human placenta labeled with Rabbit Anti TLR4/CD2...
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Formalin-fixed and paraffin embedded rat heart labeled with Rabbit Anti TLR4/CD284 Po...
SDS-PAGE (SDS) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Mouse heart lysates probed with Anti TLR4/CD284 Polyclonal Antibody, Unconjugated (AB...
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Mouse macrophages(RAW264.7) labeled with Rabbit Anti TLR4/CD284 Polyclonal Antibody, ...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Mouse splenocytes probed with Rabbit Anti-TLR4 Polyclonal Antibody .
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Image submitted by One World Lab validation program. HL60 and MCF-7 cells were staine...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Mouse macrophages(RAW264.7)labeled with Rabbit Anti TLR4/CD284 Polyclonal Antibody, U...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Toll-Like Receptor 4 (TLR4) (AA 780-830) antibody (ABIN736491) Formalin-fixed and paraffin embedded human placenta labeled with Rabbit Anti TLR4/CD2...