Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TLR4 Antikörper (AA 420-435) (Biotin)

TLR4 Reaktivität: Human WB, FACS, IHC, IF, ICC Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN2485971
  • Target Alle TLR4 Antikörper anzeigen
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Bindungsspezifität
    • 16
    • 16
    • 16
    • 15
    • 13
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 420-435
    Reaktivität
    • 181
    • 101
    • 75
    • 37
    • 23
    • 20
    • 19
    • 19
    • 5
    • 2
    • 1
    • 1
    Human
    Wirt
    • 138
    • 74
    • 8
    • 4
    Kaninchen
    Klonalität
    • 142
    • 82
    Polyklonal
    Konjugat
    • 99
    • 23
    • 21
    • 16
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR4 Antikörper ist konjugiert mit Biotin
    Applikation
    • 161
    • 130
    • 60
    • 56
    • 35
    • 32
    • 27
    • 27
    • 26
    • 24
    • 13
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~75-80 kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag).
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Protein A Purified
    Immunogen
    Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4
    Top Product
    Discover our top product TLR4 Primärantikörper
  • Applikationshinweise
    • WB (1:500)
    • IHC (1:50)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    2 μg/ml of ABIN2485971 was sufficient for detection of TLR4 in 100 ng of partial recombinant mouse TLR4 protein by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Andere Bezeichnung
    TLR4 (TLR4 Produkte)
    Synonyme
    ARMD10 antikoerper, CD284 antikoerper, TLR-4 antikoerper, TOLL antikoerper, Lps antikoerper, Ly87 antikoerper, Ran/M1 antikoerper, Rasl2-8 antikoerper, toll like receptor 4 antikoerper, toll-like receptor 4 antikoerper, TLR4 antikoerper, Tlr4 antikoerper
    Hintergrund
    The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90 kDa (6).
    Gen-ID
    7099
    NCBI Accession
    NP_612564
    UniProt
    O00206
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
Sie sind hier:
Kundenservice