anti-Maus TLR4 Antikörper für Immunohistochemistry

Recommended TLR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 4 (TLR4) Antikörper
  • ARMD10
  • CD284
  • TLR-4
  • TOLL
  • Lps
  • Ly87
  • Ran/M1
  • Rasl2-8
  • toll like receptor 4
  • toll-like receptor 4
  • TLR4
  • Tlr4
Epitop
AA 420-435
58
30
28
25
16
16
15
15
14
13
11
9
8
8
7
6
5
5
5
5
5
5
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
556
274
174
94
72
72
64
27
12
9
4
2
1
1
Wirt
Kaninchen
339
273
47
8
Klonalität
Polyklonal
Konjugat
Dieser TLR4 Antikörper ist konjugiert mit Atto 700
49
47
47
23
15
14
13
10
9
9
8
6
6
6
6
6
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
393
341
186
137
129
123
98
92
34
32
27
26
26
21
20
16
14
8
7
4
4
3
2
1
1
1
Optionen
Hersteller
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Produktnummer ABIN2485968
$ 474.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
27.753246 ABIN2485962 ICC FACS IF IHC WB Atto 488 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485964 ICC FACS IF IHC WB Atto 594 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485963 ICC FACS IF IHC WB Atto 565 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485961 ICC FACS IF IHC WB Atto 390 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485965 ICC FACS IF IHC WB Atto 633 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485967 ICC FACS IF IHC WB Atto 680 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485970 ICC FACS IF IHC WB APC Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485971 ICC FACS IF IHC WB Biotin Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485972 ICC FACS IF IHC WB FITC Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485973 ICC FACS IF IHC WB HRP Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485974 ICC FACS IF IHC WB PE-Atto 594 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485976 ICC FACS IF IHC WB PE Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485975 ICC FACS IF IHC WB PerCP Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485977 ICC FACS IF IHC WB Streptavidin Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485966 ICC FACS IF IHC WB Atto 655 Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
27.753246 ABIN2485969 ICC FACS IF IHC WB Alkaline Phosphatase (AP) Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 6
23.260653 ABIN361724 ICC FACS IF IHC WB Rabbit AA 420-435 Anmelden zum Anzeigen Polyclonal 9
21.992594 ABIN6270322 ICC IF IHC WB Rabbit IgG pSer800 Anmelden zum Anzeigen Polyclonal 0
18.992594 ABIN1173519 ICC IHC WB Rabbit IgG AA 26-269 Anmelden zum Anzeigen Polyclonal 0
18.760653 ABIN3183753 ELISA IHC WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 4 (TLR4) Antikörper
Epitop AA 420-435
(58), (30), (28), (25), (16), (16), (15), (15), (14), (13), (11), (9), (8), (8), (7), (6), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(556), (274), (174), (94), (72), (72), (64), (27), (12), (9), (4), (2), (1), (1)
Wirt Kaninchen
(339), (273), (47), (8)
Klonalität
Polyklonal
Konjugat Dieser TLR4 Antikörper ist konjugiert mit Atto 700
(49), (47), (47), (23), (15), (14), (13), (10), (9), (9), (8), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(393), (341), (186), (137), (129), (123), (98), (92), (34), (32), (27), (26), (26), (21), (20), (16), (14), (8), (7), (4), (4), (3), (2), (1), (1), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR4 Antikörper

Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN2485968) Bilder
Spezifität Detects ~75-80 kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag).
Reinigung Protein A Purified
Immunogen Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4
Plasmids, Primers & others

Target Details TLR4

Produktdetails anti-TLR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN2485968) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR4 (TLR4 Antibody Abstract)
Hintergrund The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90 kDa (6).
Gen-ID 7099
NCBI Accession NP_612564
UniProt O00206
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Handhabung Referenzen für anti-TLR4 Antikörper (ABIN2485968) Bilder zurück nach oben
Applikations-hinweise
  • WB (1:500)
  • IHC (1:50)
  • optimal dilutions for assays should be determined by the user.
Kommentare

2 μg/ml of SPC-200 was sufficient for detection of TLR4 in 100 ng of partial recombinant mouse TLR4 protein by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Referenzen für anti-TLR4 Antikörper (ABIN2485968) Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer PBS, 50 % glycerol, 0.09 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C

Referenzen für anti-TLR4 Antikörper (ABIN2485968)

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Chuang, Ulevitch: "Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells." in: Biochimica et biophysica acta, Vol. 1518, Issue 1-2, pp. 157-61, 2001

Poltorak, Ricciardi-Castagnoli, Citterio, Beutler: "Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 5, pp. 2163-7, 2000

Takeuchi, Hoshino, Kawai, Sanjo, Takada, Ogawa, Takeda, Akira: "Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components." in: Immunity, Vol. 11, Issue 4, pp. 443-51, 1999

Muzio, Natoli, Saccani, Levrero, Mantovani: "The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)." in: The Journal of experimental medicine, Vol. 187, Issue 12, pp. 2097-101, 1998

Medzhitov, Janeway: "Innate immunity: the virtues of a nonclonal system of recognition." in: Cell, Vol. 91, Issue 3, pp. 295-8, 1997

Medzhitov, Preston-Hurlburt, Janeway: "A human homologue of the Drosophila Toll protein signals activation of adaptive immunity." in: Nature, Vol. 388, Issue 6640, pp. 394-7, 1997

Bilder

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN2485968) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Atto 700) (ABIN2485968) Immunohistochemistry analysis using Rabbit Anti-TLR4 Polyclonal Antibody . Tissue: co...
Western Blotting (WB) image for anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Atto 700) (ABIN2485968) Western blot analysis of Human, Mouse Cell line lysates showing detection of TLR4 pro...
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Atto 700) (ABIN2485968) Immunohistochemistry analysis using Rabbit Anti-TLR4 Polyclonal Antibody . Tissue: Sp...
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Atto 700) (ABIN2485968) Immunohistochemistry analysis using Rabbit Anti-TLR4 Polyclonal Antibody . Tissue: sp...