anti-Human TAB1 Antikörper für Immunocytochemistry

Recommended TAB1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antikörper
  • 3'-Tab1
  • MAP3K7IP1
  • 2310012M03Rik
  • Map3k7ip1
  • b2b449Clo
  • TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1
  • TAB1
  • Tab1
Epitop
Center
31
10
10
9
9
9
8
6
5
5
5
2
2
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human
180
79
60
8
6
5
4
3
3
2
1
1
1
1
Wirt
Kaninchen
153
25
2
Klonalität
Polyklonal
Konjugat
Dieser TAB1 Antikörper ist unkonjugiert
9
9
8
6
6
6
3
2
2
2
2
2
2
2
2
2
2
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
129
73
27
20
18
14
12
11
9
3
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2855576
$ 358.60
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1859749 ICC IHC WB Rabbit IgG AA 189-439 Anmelden zum Anzeigen Polyclonal 0
1 ABIN214510 ICC IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1739871 ICC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN4357485 ICC IF IHC IHC (p) Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN1031115 ICC ELISA WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN298197 ICC WB Goat IgG AA 7-159 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4357488 ICC IF WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN1583785 ICC ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN2959957 ICC IF ELISA WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN1887777 ICC ELISA WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN4357487 ELISA ICC IF WB Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antikörper
Epitop Center
(31), (10), (10), (9), (9), (9), (8), (6), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(180), (79), (60), (8), (6), (5), (4), (3), (3), (2), (1), (1), (1), (1)
Wirt Kaninchen
(153), (25), (2)
Klonalität
Polyklonal
Konjugat Dieser TAB1 Antikörper ist unkonjugiert
(9), (9), (8), (6), (6), (6), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(129), (73), (27), (20), (18), (14), (12), (11), (9), (3), (3), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TAB1 Antikörper

Target Details TAB1 Anwendungsinformationen Handhabung Bilder
Kreuzreaktivität Maus, Huhn, Schwein
Kreuzreaktivität (Details) Mouse (96 %), Chicken (90 %), Pig (96 %)
Produktmerkmale Rabbit Polyclonal antibody to TAB1 (TGF-beta activated kinase 1/MAP3K7 binding protein 1)
TAB1 antibody
Reinigung Purified by antigen-affinity chromatography.
Immunogen Recombinant protein encompassing a sequence within the center region of human TAB1. The exact sequence is proprietary.
Isotyp IgG
Plasmids, Primers & others

Target Details TAB1

Produktdetails anti-TAB1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TAB1 (TAB1 Antibody Abstract)
Hintergrund The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht 55 kDa
Gen-ID 10454
Pathways TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TAB1 Antikörper Target Details TAB1 Handhabung Bilder zurück nach oben
Applikations-hinweise Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
Kommentare

Positive Control: TAB1 tansfected 293T cell

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 0.26 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Konservierungs-mittel Thimerosal (Merthiolate)
Vorsichtsmaßnahmen This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Bilder

Produktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (Center) antibody (ABIN2855576) WB Image Western Blot analysis of TAB1 expression in transfected 293T cell line by MA...
Immunofluorescence (IF) image for anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (Center) antibody (ABIN2855576) ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde...