anti-Human IRF7 Antikörper für Western Blotting

Recommended IRF7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Interferon Regulatory Factor 7 (IRF7) Antikörper
  • wu:fl24c03
  • zgc:66043
  • zgc:77947
  • IRF7
  • irf7
  • IRF-7H
  • IRF7A
  • IRF7B
  • IRF7C
  • IRF7H
  • interferon regulatory factor 7
  • irf7
  • IRF7
  • Irf7
Epitop
pSer471, pSer472, AA 450-490
26
23
15
14
14
14
7
5
5
4
4
3
2
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
154
61
57
3
2
2
2
2
1
1
Wirt
Kaninchen
111
43
Klonalität
Polyklonal
Konjugat
Dieser IRF7 Antikörper ist unkonjugiert
7
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
108
53
27
26
25
11
7
5
5
2
2
1
1
1
Optionen
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Bilder

Produktnummer ABIN742703
$ 351.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
16.563305 ABIN3020651 FACS IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
16.563305 ABIN933734 ELISA WB Mouse IgG1 kappa AA 1-150 Anmelden zum Anzeigen 3D9 0
14.5 ABIN682603 IF (p) IHC (p) WB Rabbit IgG AA 420-470 Anmelden zum Anzeigen Polyclonal 3
13.751972 ABIN5518764 IHC (p) WB Rabbit IgG AA 31-67, N-Term Anmelden zum Anzeigen Polyclonal 0
13.751972 ABIN263914 EIA IHC (p) WB Mouse IgG1 AA 1-150, N-Term Anmelden zum Anzeigen 3D9 3
12.811332 ABIN6388341 ELISA WB Rabbit IgG AA 410-490 Anmelden zum Anzeigen Polyclonal 0
12.811332 ABIN808834 ELISA WB Mouse AA 1-150 Anmelden zum Anzeigen P3D9AT 0
10.751972 ABIN2736992 FACS IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10 ABIN6391259 ELISA IHC IHC (p) WB Mouse IgG1, kappa AA 1-150 Anmelden zum Anzeigen 3D9 0
9.251972 ABIN2475148 WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 2
9.251972 ABIN2475145 WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 2
9.251972 ABIN532980 ELISA WB Mouse IgG1 Anmelden zum Anzeigen 3D9 3
9.251972 ABIN550400 WB Rabbit Anmelden zum Anzeigen Polyclonal 3
9.251972 ABIN550401 WB Rabbit Anmelden zum Anzeigen Polyclonal 3
7.751972 ABIN2780566 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
7.751972 ABIN6262657 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
7.751972 ABIN5557323 IF (cc) WB Rabbit IgG Anmelden zum Anzeigen 2A1 0
7.751972 ABIN1030964 IHC ELISA WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
7.751972 ABIN1030452 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
7 ABIN318755 WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 2

General

Antigen Interferon Regulatory Factor 7 (IRF7) Antikörper
Epitop pSer471, pSer472, AA 450-490
(26), (23), (15), (14), (14), (14), (7), (5), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(154), (61), (57), (3), (2), (2), (2), (2), (1), (1)
Wirt Kaninchen
(111), (43)
Klonalität
Polyklonal
Konjugat Dieser IRF7 Antikörper ist unkonjugiert
(7), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(108), (53), (27), (26), (25), (11), (7), (5), (5), (2), (2), (1), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-IRF7 Antikörper

Target Details IRF7 Anwendungsinformationen Handhabung Referenzen für anti-IRF7 Antikörper (ABIN742703) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human IRF7 around the phosphorylation site of Ser471/472
Isotyp IgG
Plasmids, Primers & others

Target Details IRF7

Produktdetails anti-IRF7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-IRF7 Antikörper (ABIN742703) Bilder zurück nach oben
Antigen
Andere Bezeichnung Irf7 (IRF7 Antibody Abstract)
Hintergrund

Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. Exists in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization where along with other coactivators it can activate transcription of the type I IFN and ISG genes. Can also play a role in regulating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or through induction of IRF1. Binds to the Q promoter (Qp) of EBV nuclear antigen 1 a (EBNA1) and may play a role in the regulation of EBV latency. Can activate distinct gene expression programs in macrophages and regulate the anti-tumor properties of primary macrophages.

Subcellular location: Nucleus

Synonyms: IRF7A, IRF7B, IRF7C, IRF7H, IRF-7H, Interferon regulatory factor 7, IRF-7, IRF7

Gen-ID 3665
UniProt Q92985
Pathways TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagie

Anwendungsinformationen

Produktdetails anti-IRF7 Antikörper Target Details IRF7 Handhabung Referenzen für anti-IRF7 Antikörper (ABIN742703) Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-IRF7 Antikörper Target Details IRF7 Anwendungsinformationen Referenzen für anti-IRF7 Antikörper (ABIN742703) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen für anti-IRF7 Antikörper (ABIN742703)

Produktdetails anti-IRF7 Antikörper Target Details IRF7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Le Bel, Gosselin: "Leukotriene B4 Enhances NOD2-Dependent Innate Response against Influenza Virus Infection." in: PLoS ONE, Vol. 10, Issue 10, pp. e0139856, 2015 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)). Weitere Details: Sample: Lung

Han, Choi, Uyangaa, Kim, Kim, Kim, Kim, Eo: "Distinct dictation of Japanese encephalitis virus-induced neuroinflammation and lethality via triggering TLR3 and TLR4 signal pathways." in: PLoS pathogens, Vol. 10, Issue 9, pp. e1004319, 2014 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Menasria, Boivin, Lebel, Piret, Gosselin, Boivin: "Both TRIF and IPS-1 Adaptor Proteins Contribute to the Cerebral Innate Immune Response against Herpes Simplex Virus 1 Infection." in: Journal of virology, Vol. 87, Issue 13, pp. 7301-8, 2013 Von den Autoren verwendete Methode: Western Blotting (WB)

Bilder

Produktdetails anti-IRF7 Antikörper Target Details IRF7 Anwendungsinformationen Handhabung Referenzen für anti-IRF7 Antikörper (ABIN742703) zurück nach oben
Bilder des Herstellers
SDS-PAGE (SDS) image for anti-Interferon Regulatory Factor 7 (IRF7) (AA 450-490), (pSer471), (pSer472) antibody (ABIN742703) Lane 1: mouse embryo lysates Lane 2: mouse brain lysates probed with Anti Phospho-IRF...
Immunohistochemistry (IHC) image for anti-Interferon Regulatory Factor 7 (IRF7) (AA 450-490), (pSer471), (pSer472) antibody (ABIN742703) Formalin-fixed and paraffin embedded mouse pancreas tissue labeled with Anti-Phospho-...
Immunohistochemistry (IHC) image for anti-Interferon Regulatory Factor 7 (IRF7) (AA 450-490), (pSer471), (pSer472) antibody (ABIN742703) Formalin-fixed and paraffin embedded rat spleen tissue labeled with Anti-Phospho-IRF7...
Western Blotting (WB) image for anti-Interferon Regulatory Factor 7 (IRF7) (AA 450-490), (pSer471), (pSer472) antibody (ABIN742703) Lane 1: Mouse uterus lysates, Lane 2: Mouse large intestine lysates probed with IRF7 ...