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Human CSF1 Protein expressed in Escherichia coli (E. coli) - ABIN413611
Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ... in Annals of the rheumatic diseases 2010
the high level of colony-stimulating factor 1 expression during bovine pregnancy in uteroplacental tissues is consistent with its proposed role in placental physiology
results suggest that leukemia inhibitory factor (zeige LIF Proteine) and macrophage-colony stimulating factor (zeige CSF2 Proteine) are produced in the endometrium and may play different roles in early and mid-pregnancy
These results indicate that BARF1 blockade of CSF-1 signaling is an important immune evasion strategy for efficient acute EBV infection and a significant determinant for virus setpoint during persistent EBV infection.
the complete sequencing of M-CSF (zeige CSF1R Proteine) genes, gene organizaztion,splice varaiants, gene expression, and M-CSF (zeige CSF1R Proteine) role in the immune system
miR (zeige MLXIP Proteine)-1207-5p and CSF1 expression levels and their relationship with lung cancer survival and metastasis status were assayed by means of a lung cancer tissue microarray.
Upregulation of GM-CSF (zeige CSF2 Proteine) and M-CSF production by endothelial cells, an effect that appears to be mediated by NF-kappaB (zeige NFKB1 Proteine) and to be independent of IL-1 (zeige IL1A Proteine), may be an additional mechanism through which IL-33 (zeige IL33 Proteine) contributes to inflammatory activation of the vessel wall.
High CSF-1 expression is associated with Breast Cancer.
Nucleolin (zeige NCL Proteine) both forms an mRNP complex with the eIF4G (zeige EIF4G1 Proteine) and CSF-1 mRNA, and is co-localized with the eIF4G (zeige EIF4G1 Proteine) in the cytoplasm further supporting nucleolin's role in translational regulation.
study, therefore, provided insights into the sequence-structure-function relationships of the M-CSF/c-FMS (zeige CSF1R Proteine) interaction and of ligand/receptor tyrosine kinase (zeige RET Proteine) interactions in general.
Therefore, our findings indicate that CSF1 signaling is oncogenic during gliomagenesis through a mechanism distinct from modulating glioma-associated microglia/macrophage polarization status
High CSF1 expression is associated with breast cancer.
M-CSF has been shown to be comparable to CA15-3 and VEGF (zeige VEGFA Proteine), specificity, and AUC values only in stages III and IV of BC.
M-CSF macrophage conversion into foam cells reduces their proinflammatory responses to classical M1-polarizing activation
This can be achieved by either blocking the EGF (zeige EGF Proteine) or CSF-1 receptors or supressing the EGF (zeige EGF Proteine) or CSF-1 signal.
lymphatic endothelial cells cause bone destruction in vivo in mice by secreting M-CSF (zeige CSF1R Proteine), which promotes osteoclasts formation and activation.
NMB or NMBR silencing inhibited M-CSF (zeige CSF1R Proteine)/c-Fms (zeige CSF1R Proteine)-mediated downstream signaling pathways like activation of ERK (zeige EPHB2 Proteine) and Akt (zeige AKT1 Proteine) and induction of D-type cyclins, cyclin D1 (zeige CCND1 Proteine) and D2.
address which CSF-1-activated pathways are involved in transmitting the lineage-instructive signal in primary bone marrow-derived GM progenitors.
study concludes that M-CSF (zeige CSF1R Proteine) is critical to host defenses against bacterial pneumonia by mediating survival and antimicrobial functions of mononuclear phagocytes in the lungs and liver.
study, therefore, provided insights into the sequence-structure-function relationships of the M-CSF (zeige CSF1R Proteine)/c-FMS (zeige CSF1R Proteine) interaction and of ligand/receptor tyrosine kinase (zeige ERBB3 Proteine) interactions in general.
study shows that PLCgamma1 (zeige PLCG1 Proteine) controls osteoclast numbers via a CSF-1-dependent DAG/beta-catenin (zeige CTNNB1 Proteine)/cyclinD1 pathway.
study concludes that Langerhans cells require IL-34 (zeige IL34 Proteine) when residing in fully differentiated and anatomically intact skin epidermis, but rely on neutrophil-derived CSF1 during inflamma
Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF (zeige CSF2 Proteine)) and Macrophage Colony Stimulating Factor (zeige CSF2 Proteine) (M-CSF (zeige CSF1R Proteine)) Grown Macrophages Derived from Murine Bone Marrow Cells
Hematopoietic cells can be induced by M-CSF (zeige CSF1R Proteine) to dedifferentiate to multipotent stem cells.
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.
macrophage colony-stimulating factor 1
, colony stimulating factor 1 (macrophage)
, macrophage colony-stimulating factor 1-like
, colony-stimulating factor 1