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anti-Human Nucleolin Antikörper:
anti-Mouse (Murine) Nucleolin Antikörper:
anti-Rat (Rattus) Nucleolin Antikörper:
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Human Polyclonal Nucleolin Primary Antibody für ChIP, EM - ABIN153181
Hanakahi, Dempsey, Li, Maizels: Nucleolin is one component of the B cell-specific transcription factor and switch region binding protein, LR1. in Proceedings of the National Academy of Sciences of the United States of America 1997
Show all 17 Pubmed References
Human Polyclonal Nucleolin Primary Antibody für ICC, IF - ABIN151419
Wu, Shen, Newburger: Recognition and binding of the human selenocysteine insertion sequence by nucleolin. in Journal of cellular biochemistry 2000
Show all 2 Pubmed References
Human Polyclonal Nucleolin Primary Antibody für IHC, IP - ABIN151659
Tan, Glen, Töpf, Hall, OSullivan, Sneddon, Wren, Avery, Lewis, ten Dijke, Arthur, Goodship, Keavney: Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation. in Human mutation 2012
Results found that prostate circulating tumor cells (CTCs) as a population have an increased level of total nucleolin expression compared to white blood cells. Additionally, there was a distinct nucleolin staining pattern and localization in CTCs.
this results show that nucleolin increases colony formation and anchorage-independent growth of ErbB2 (zeige ERBB2 Antikörper)-overexpressing cells, and that nucleolin overexpression in ErbB2 (zeige ERBB2 Antikörper)-positive breast cancer patients is associated with reduced patient survival rates and increased disease-risk
C23 has a role in promoting tumorigenesis via suppressing p53 (zeige TP53 Antikörper) activity
NCL (zeige CLN5 Antikörper) was associated with bipolar disorder.
Nucleolin both forms an mRNP complex with the eIF4G (zeige EIF4G1 Antikörper) and CSF-1 (zeige CSF1 Antikörper) mRNA, and is co-localized with the eIF4G (zeige EIF4G1 Antikörper) in the cytoplasm further supporting nucleolin's role in translational regulation.
Identified the regulator of ribosome production nucleolin (NCL) as over-expressed in AML (zeige RUNX1 Antikörper) blasts. Moreover, we found in two series that high NCL (zeige CLN5 Antikörper) mRNA expression level was associated with a poor overall survival, particular in elderly patients.
Data suggest a 216-nucleotide proximal cis (zeige CISH Antikörper)-element in LIF (zeige LIF Antikörper) mRNA exhibits mRNA destabilizing potential; on exposure to carcinogen PMA (phorbol-12-myristate-13-acetate), this cis (zeige CISH Antikörper)-element exhibits mRNA stabilizing activity. PMA induces nucleo-cytoplasmic translocation of both nucleolin and PCBP1 (zeige PCBP1 Antikörper), 2 trans-acting factors that bind to and stabilize LIF (zeige LIF Antikörper) mRNA. [LIF (zeige LIF Antikörper) = leukemia inhibitory factor (zeige LIF Antikörper); PCBP1 (zeige PCBP1 Antikörper) = poly(rC) binding protein 1 (zeige PCBP1 Antikörper)]
Data suggest that C11orf98 microprotein, NPM1 (zeige NPM1 Antikörper), and nucleolin interact and colocalize in the cell nucleolus. (C11orf98 = chromosome 11 open reading frame 98 protein; NPM1 (zeige NPM1 Antikörper) = nucleophosmin 1 (zeige NPM1 Antikörper))
nucleolin inhibition is a new anti-pancreatic cancer therapeutic strategy that dually blocks tumor progression and normalizes tumor vasculature in pancreatic ductal adenocarcinoma
It has been found that during microtubule growth phases, nucleolin affects both the speed and life time of microtubule polymerization.
subcellular sequestration of nucleolin or importin beta1 enhances axonal growth and causes a subcellular shift in protein synthesis
Data indicate alpha-P85 (zeige ECM1 Antikörper) Subunit, PI-3K (p85alpha) as a positive regulator of epidermal growth factor receptor (EGFR (zeige EGFR Antikörper)) expression and cell malignant transformation via nucleolin-dependent mechanism.
Nucleolin protects macrophages from oxLDL-induced foam cell formation in hyperlipidemia through up-regulating ABCA1 (zeige ABCA1 Antikörper) expression.
Nucleolin Acts as a Scavenger Receptor for Acetylated Low-Density Lipoprotein on Macrophages
Nucleolin is a receptor for maleylated-bovine serum albumin (zeige ALB Antikörper) on macrophages
Lrrc34, a novel nucleolar protein (zeige MCRS1 Antikörper), interacts with npm1 (zeige GJA1 Antikörper) and ncl and has an impact on pluripotent stem cells
results indicate that nucleolin is a receptor that allows macrophages to recognize toxic Advanced glycosylation end-products.
results for the first time demonstrate that nucleolin-SUMO at K294R plays a critical role in its nucleus sequestration and gadd45alpha (zeige GADD45A Antikörper) mRNA binding activity.
Nucleolin-FGF1 interaction is critical for the intranuclear phosphorylation of FGF1 by PKCdelta and thereby the regulation of nuclear export of FGF1.
Data show that si-RNA induced down-regulation of FUT1 (zeige FUT1 Antikörper) and FUT2 (zeige FUT2 Antikörper) reduced expression of fucosylated nucleolin glycoforms and their exposure at the cell surface.
Suggest that during heart disease nucleolin is reactivated to mobilize conserved aspects of chromatin remodeling and gene expression.
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
, protein C23