CXCL1 Protein

Produktnummer ABIN987891

Produktdetails

Target: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Sequenz: APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV P

Produktmerkmale: Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using rat neutrophils is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.

Reinheit: > 97 % by SDS-PAGE and HPLC analyses.

Endotoxin-Niveau: Level Less than 1EU/µg of rRtGRO/CXCL1 as determined by LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Lagerung: 4 °C

Antigendetails

Target: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Andere Bezeichnung: GRO alpha/cxcl1 (CXCL1 Produkte)

Synonyme: FSP Protein, GRO1 Protein, GROa Protein, MGSA Protein, MGSA-a Protein, NAP-3 Protein, SCYB1 Protein, CINC-1 Protein, Gro1 Protein, CXCL1 Protein, Sdf1 Protein, Fsp Protein, KC Protein, Mgsa Protein, N51 Protein, Scyb1 Protein, gro Protein, GRO Protein, Gro Protein, C-X-C motif chemokine ligand 1 Protein, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Protein, C-X-C motif chemokine ligand 12 Protein, chemokine (C-X-C motif) ligand 1 Protein, CXCL1 Protein, Cxcl1 Protein, Cxcl12 Protein, GRO1 Protein

Hintergrund: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. Synonym: GRO alpha/CXCL1, Rat. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.

Molekulargewicht: 7.8 kDa, a single, non-glycosylated polypeptide chain containing 72 amino acids.

Pathways: Autophagie