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TACI Protein

TNFRSF13B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935869
  • Target Alle TACI (TNFRSF13B) Proteine anzeigen
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 13
    • 5
    Human
    Quelle
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL PGLKLSADQV
    Produktmerkmale
    Purified recombinant Human TACI protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to bl °Ck human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 µg/mL.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product TNFRSF13B Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    Andere Bezeichnung
    TACI (TNFRSF13B Produkte)
    Synonyme
    CD267 Protein, CVID Protein, CVID2 Protein, RYZN Protein, TACI Protein, TNFRSF14B Protein, TNFRSF13B Protein, 1200009E08Rik Protein, Taci Protein, TNF receptor superfamily member 13B Protein, tumor necrosis factor receptor superfamily, member 13b Protein, TNFRSF13B Protein, Tnfrsf13b Protein
    Hintergrund
    TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI binds to both APRIL and BAFF and can stimulate the activation of transcription factors, NF-kappaB, AP-1, and mediates calcineurin dependent activation of NF-AT (nuclear-factor of activated T cells). TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRILstimulated proliferation of primary B-cells by blocking the binding of APRIL to the membrane anchored TACI receptor.
    Alternative Names: TNFRSF13B protein, Transmembrane activator and CAML interactor protein
    Molekulargewicht
    17.8 kDa
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