TACI Protein (AA 1-166) (His tag)

Produktnummer ABIN1880646

Produktdetails

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-166

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses TACI Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human T-lymphocyte Surface Antigen Ly-9/SLAMF3/CD229 (C-6His)

Sequenz: KDSAPTVVSG ILGGSVTLPL NISVDTEIEN VIWIGPKNAL AFARPKENVT IMVKSYLGRL DITKWSYSLC ISNLTLNDAG SYKAQINQRN FEVTTEEEFT LFVYEQLQEP QVTMKSVKVS ENFSCNITLM CSVKGAEKSV LYSWTPREPH ASESNGGSIL TVSRTPCDPD LPYICTAQNP VSQRSSLPVH VGQFCTDPGA SRGGTTGETV VGVLGEPVTL PLALPACRDT EKVVWLFNTS IISKEREEAA TADPLIKSRD PYKNRVWVSS QDCSLKISQL KIEDAGPYHA YVCSEASSVT SMTHVTLLIY RRLRKPKITW SLRHSEDGIC RISLTCSVED GGNTVMYTWT PLQKEAVVSQ GESHLNVSWR SSENHPNLTC TASNPVSRSS HQFLSENICS GPERNTKHHH HHH

Produktmerkmale: Recombinant Human Tumor necrosis factor receptor superfamily member 13B/TNFRSF13B is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-His166) of Human TNFRSF13B fused with a polyhistidine tag and FC tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Andere Bezeichnung: TNFRSF13B (TNFRSF13B Produkte)

Synonyme: CD267 Protein, CVID Protein, CVID2 Protein, RYZN Protein, TACI Protein, TNFRSF14B Protein, TNFRSF13B Protein, 1200009E08Rik Protein, Taci Protein, TNF receptor superfamily member 13B Protein, tumor necrosis factor receptor superfamily, member 13b Protein, TNFRSF13B Protein, Tnfrsf13b Protein

Sub Type: Fusionprotein

Hintergrund: Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), is also known as Transmembrane activator and CAML interactorand, CD267 and TACI. TNFRSF13B is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. TNFRSF13B is highly expressed in spleen, small intestine, thymus and peripheral blood leukocytes. TNFRSF13B mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. TNFRSF13B is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. Defects in TNFRSF13B are the cause of immunodeficiency common variable type 2 (CVID2) and cause of immunoglobulin A deficiency 2 (IGAD2).
Alternative Names: Tumor necrosis factor receptor superfamily member 13B, TNFRSF13B, Transmembrane activator, CAML interactorand, CD267,TACI.

Molekulargewicht: 45.6 kDa

UniProt: Q9HBG7