PTPN1 Protein

Produktnummer ABIN934895

Produktdetails

Target: PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Sequenz: MEMEKEFEQI DKSGSWAAIY QDIRHEASDF PCRVAKLPKN KNRNRYRDVS PFDHSRIKLH QEDNDYINAS LIKMEEAQRS YILTQGPLPN TCGHFWEMVW EQKSRGVVML NRVMEKGSLK CAQYWPQKEE KEMIFEDTNL KLTLISEDIK SYYTVRQLEL ENLTTQETRE ILHFHYTTWP DFGVPESPAS FLNFLFKVRE SGSLSPEHGP VVVHCSAGIG RSGTFCLADT CLLLMDKRKD PSSVDIKKVL LEMRKFRMGL IQTADQLRFS YLAVIEGAKF IMGDSSVQDQ WKELSHEDLE PPPEHIPPPP RPPKRILEPH N

Produktmerkmale: Purified recombinant Human PTP1 B protein
Expression System: E.coli
Bioactivity: 10,000units/mg of PTP1B
Molecular weight on SDS-PAGE will appear higher.

Reinheit: > 95 % pure

Anwendungsinformationen

Applikationshinweise: PTP1B protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Kommentare:

One unit will hydrolyze 1 nM of p-nitrophenyl-phosphatate per minute at pH 7.4 at 37 °C using 10 mM of substrate

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 25 mM Tris-HCl, pH7.5, containing 2 mM beta-mercaptoethanol, 1 mM EDTA.1 mMDTT, and 20 % glycerol.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))

Andere Bezeichnung: PTP1B (PTPN1 Produkte)

Synonyme: PTPN1 Protein, PTP1B Protein, PTP-1B Protein, PTP-HA2 Protein, Ptp Protein, ptp1b Protein, wu:fk54h03 Protein, CPTP1 Protein, protein tyrosine phosphatase, non-receptor type 1 Protein, protein tyrosine phosphatase, non-receptor type 1 L homeolog Protein, PTPN1 Protein, Ptpn1 Protein, ptpn1 Protein, ptpn1.L Protein

Hintergrund: The protein coding region of the catalytic domain of PTP-1B was cloned into an E. coli expression vector. The catalytic domain of PTP-1B was overexpressed in E. coli as a soluble protein, and it was purified by conventional column chromatographic techniques.
Alternative Names: PTPN1 protein, PTPB 1 protein, Protein Tyrosine Phosphatase Non Receptor Type-1, PTPB-1, Protein Tyrosine Phosphatase 1B protein, PTP1B protein, PTPB 1, PTP-1B protein, EC 3.1.3.48 protein, PTP1B, PTPB-1 protein, Protein tyrosine phosphatase non-receptor type 1 protein, Protein-tyrosine phosphatase1B protein, Tyrosine-protein phosphatase non-receptor type 1 protein

Molekulargewicht: 37.3 kDa (321 AA)

Pathways: TLR Signalweg, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling