TNF alpha Protein
Kurzübersicht für TNF alpha Protein (ABIN7937250)
Target
Alle TNF alpha Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Canine Tumor Necrosis Factor-alpha/TNFSF2
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Sequenz
- VKSSSRTPSD KPVAHVVANP EAEGQLQWLS RRANALLANG VELTDNQLIV PSDGLYLIYS QVLFKGQGCP STHVLLTHTI SRFAVSYQTK VNLLSAIKSP CQRETPEGTE AKPWYEPIYL GGVFQLEKGD RLSAEINLPN YLDFAESGQV YFGIIAL
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 1 EU/ug of rCaTNF-alpha as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 x106 IU/mg in the presence of actinomycin D.
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Kommentare
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Approximately 17.3 kDa, a single non-glycosylated polypeptide chain containing 157 amino acids.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Haltbarkeit
- 12 months
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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Andere Bezeichnung
- Tumor Necrosis Factor-alpha
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Molekulargewicht
- 17.3 kDa
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Gen-ID
- 403922
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UniProt
- P51742
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Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
Target
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