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NTRK3 Protein (Fc Tag,His tag)

NTRK3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
Produktnummer ABIN7534485
  • Target Alle NTRK3 Proteine anzeigen
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 17
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 9
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses NTRK3 Protein ist gelabelt mit Fc Tag,His tag.
    Verwendungszweck
    Active Recombinant Human Trk-C/NTRK3 Protein
    Sequenz
    CPANCVCSKT EINCRRPDDG NLFPLLEGQD SGNSNGNASI NITDISRNIT SIHIENWRSL HTLNAVDMEL YTGLQKLTIK NSGLRSIQPR AFAKNPHLRY INLSSNRLTT LSWQLFQTLS LRELQLEQNF FNCSCDIRWM QLWQEQGEAK LNSQNLYCIN ADGSQLPLFR MNISQCDLPE ISVSHVNLTV REGDNAVITC NGSGSPLPDV DWIVTGLQSI NTHQTNLNWT NVHAINLTLV NVTSEDNGFT LTCIAENVVG MSNASVALTV YYPPRVVSLE EPELRLEHCI EFVVRGNPPP TLHWLHNGQP LRESKIIHVE YYQEGEISEG CLLFNKPTHY NNGNYTLIAK NPLGTANQTI NGHFLKEPFP ESTDNFILFD EVSPTPPITV THKPEED
    Spezifität
    Cys32-Asp428
    Reinheit
    > 97 % by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    < 1.0 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human NTF3 at 2 μg/mL (100 μL/well) can bind Recombinant human TrkC with a linear range of 22-90 ng/mL.
    Top Product
    Discover our top product NTRK3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    Andere Bezeichnung
    Trk-C/NTRK3 (NTRK3 Produkte)
    Synonyme
    TRKC Protein, gp145(trkC) Protein, trkC Protein, AW125844 Protein, Ntrk3_tv3 Protein, TrkC Protein, neurotrophic receptor tyrosine kinase 3 Protein, neurotrophic tyrosine kinase, receptor, type 3 Protein, NTRK3 Protein, Ntrk3 Protein
    Hintergrund

    Description: NT-3 growth factor receptor also known as neurotrophic tyrosine kinase receptor type 3 or TrkC tyrosine kinase or Trk-C receptor, is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in TrkC encoding gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

    Name: NTRK3,GP145-TrkC,TRKC,gp145(trkC)

    Gen-ID
    4916
    UniProt
    Q16288
    Pathways
    RTK Signalweg, Neurotrophin Signalübertragung, Regulation of Cell Size
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