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IL18BP Protein (Fc Tag,His tag)

IL18BP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
Produktnummer ABIN7534133
  • Target Alle IL18BP Proteine anzeigen
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 11
    • 6
    • 3
    • 2
    • 1
    Human
    Quelle
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL18BP Protein ist gelabelt mit Fc Tag,His tag.
    Verwendungszweck
    Active Recombinant Human IL-18BP Protein
    Sequenz
    TPVSQTTTAA TASVRSTKDP CPSQPPVFPA AKQCPALEVT WPEVEVPLNG TLSLSCVACS RFPNFSILYW LGNGSFIEHL PGRLWEGSTS RERGSTGTQL CKALVLEQLT PALHSTNFSC VLVDPEQVVQ RHVVLAQLWA GLRATLPPTQ EALPSSHSSP QQQG
    Spezifität
    Thr31-Gly194
    Reinheit
    > 95 % by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human IL18BP at 2 μg/mL (100 μL/well) can bind IL18 with a linear range of 0.128-47.02 ng/mL.
    Top Product
    Discover our top product IL18BP Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    Andere Bezeichnung
    IL-18BP (IL18BP Produkte)
    Synonyme
    IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
    Hintergrund

    Description: Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease.

    Name: IL18BP,IL18BPa

    Gen-ID
    10068
    UniProt
    O95998
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