IL18BP Protein (AA 31-194) (His-Avi Tag,Biotin)
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- Target Alle IL18BP Proteine anzeigen
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 31-194
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL18BP Protein ist gelabelt mit His-Avi Tag,Biotin.
- Verwendungszweck
- Biotinylated Human IL-18BP Protein
- Sequenz
- Thr31-Gly194
- Produktmerkmale
- Recombinant Biotinylated Human IL-18BP Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr31-Gly194.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-18 at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-18BP, His Tag with the EC50 of 6.1ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product IL18BP Protein
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Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (Fc Tag)
IL18BP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His tag)IL18BP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (His tag)IL18BP Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (Fc Tag)IL18BP Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (GST tag)IL18BP Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His tag)Crystallography grade IL18BP Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (His tag)Crystallography grade IL18BP Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Andere Bezeichnung
- IL-18BP (IL18BP Produkte)
- Synonyme
- IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
- Hintergrund
- Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
- Molekulargewicht
- 20.5 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Tris-Bis PAGE result.
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