IL18BP Protein (His tag)
-
- Target Alle IL18BP Proteine anzeigen
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Protein-Typ
- Recombinant
-
Spezies
- Maus
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL18BP Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse IL-18BP Protein
- Sequenz
- TSAPQTTATV LTGSSKDPCS SWSPAVPTKQ YPALDVIWPE KEVPLNGTLT LSCTACSRFP YFSILYWLGN GSFIEHLPGR LKEGHTSREH RNTSTWLHRA LVLEELSPTL RSTNFSCLFV DPGQVAQYHI ILAQLWDGLK TAPSPSQETL SSHSPVSRSA GPGVA
- Spezifität
- Thr29-Ala193
- Reinheit
- > 95 % by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- <0.1EU/μg
- Top Product
- Discover our top product IL18BP Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
-
- Target
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Andere Bezeichnung
- IL-18BP (IL18BP Produkte)
- Synonyme
- IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
- Hintergrund
-
Description: Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. The adjacently located family members IL18 Receptor 1 (IL18R1) and IL18 receptor accessory protein (IL18RAP) may also be important in the development of asthma and atopy. IL-18 binding protein (IL-18BP) was only moderately elevated, resulting in a high level of biologically active free IL-18 in HPS. A severe IL-18/IL-18BP imbalance results in Th-1 lymphocyte and macrophage activation, which escapes control by NK-cell cytotoxicity and may allow for secondary HPS in patients with underlying diseases.
Name: MC54L,Igifbp,IL-18BP,IL18BP
- Gen-ID
- 16068
- UniProt
- Q9Z0M9
-