IL1RL1 Protein (Fc Tag)

Produktnummer ABIN7536248

Produktdetails

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL1RL1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Mouse IL1RL1 Protein

Sequenz: SKSSWGLENE ALIVRCPQRG RSTYPVEWYY SDTNESIPTQ KRNRIFVSRD RLKFLPARVE DSGIYACVIR SPNLNKTGYL NVTIHKKPPS CNIPDYLMYS TVRGSDKNFK ITCPTIDLYN WTAPVQWFKN CKALQEPRFR AHRSYLFIDN VTHDDEGDYT CQFTHAENGT NYIVTATRSF TVEEKGFSMF PVITNPPYNH TMEVEIGKPA SIACSACFGK GSHFLADVLW QINKTVVGNF GEARIQEEEG RNESSSNDMD CLTSVLRITG VTEKDLSLEY DCLALNLHGM IRHTIRLRRK QPIDHR

Spezifität: Ser27-Arg332

Reinheit: > 92 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <0.1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Andere Bezeichnung: IL1RL1 (IL1RL1 Produkte)

Synonyme: DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein

Hintergrund:

Description: IL-1 receptor-like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.

Name: T1, St2, DER4, Ly84, ST2L, Fit-1, T1/ST2, St2-rs1,IL1RL1

Gen-ID: 17082

UniProt: P14719