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IL1RL1 Protein (AA 1-328, Isoform 2) (Fc Tag)

IL1RL1 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
Produktnummer ABIN1344266
  • Target Alle IL1RL1 Proteine anzeigen
    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Isoform 2, AA 1-328
    Spezies
    • 20
    • 11
    Human
    Quelle
    • 14
    • 5
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL1RL1 Protein ist gelabelt mit Fc Tag.
    Applikation
    SDS-PAGE (SDS)
    Spezifität
    Binds to human IL-33.
    Kreuzreaktivität
    Human
    Produktmerkmale
    Signal peptide and the sequence of isoform 2 of human ST2 (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1.
    Reinheit
    >90 % (SDS-PAGE)
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product IL1RL1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Interacts with human IL-33.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.2.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Working aliquots are stable for up to 3 months when stored at -20°C.
    Haltbarkeit
    3 months
  • Target
    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
    Andere Bezeichnung
    ST2 (IL1RL1 Produkte)
    Synonyme
    DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein
    Hintergrund
    The ST2 (Interleukin-1 receptor-like 1, Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
    Molekulargewicht
    ~90kDa (SDS-PAGE)
    UniProt
    Q01638
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