HHIP Protein (His tag)

Produktnummer ABIN7534321

Produktdetails

Target: HHIP (Hedgehog Interacting Protein (HHIP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses HHIP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Hedgehog-interacting protein/HHIP Protein

Sequenz: FFEGDAKFGE RNEGSGARRR RCLNGNPPKR LKRRDRRMMS QLELLSGGEM LCGGFYPRLS CCLRSDSPGL GRLENKIFSV TNNTECGKLL EEIKCALCSP HSQSLFHSPE REVLERDLVL PLLCKDYCKE FFYTCRGHIP GFLQTTADEF CFYYARKDGG LCFPDFPRKQ VRGPASNYLD QMEEYDKVEE ISRKHKHNCF CIQEVVSGLR QPVGALHSGD GSQRLFILEK EGYVKILTPE GEIFKEPYLD IHKLVQSGIK GGDERGLLSL AFHPNYKKNG KLYVSYTTNQ ERWAIGPHDH ILRVVEYTVS RKNPHQVDLR TARVFLEVAE LHRKHLGGQL LFGPDGFLYI ILGDGMITLD DMEEMDGLSD FTGSVLRLDV DTDMCNVPYS IPRSNPHFNS TNQPPEVFAH GLHDPGRCAV DRHPTDININ LTILCSDSNG KNRSSARILQ IIKGKDYESE PSLLEFKPFS NGPLVGGFVY RGCQSERLYG SYVFGDRNGN FLTLQQSPVT KQWQEKPLCL GTSGSCRGYF SGHILGFGED ELGEVYILSS SKSMTQTHNG KLYKIVDPKR PLMPEECRAT VQPAQTLTSE CSRLCRNGYC TPTGKCCCSP GWEGDFCRTA KCEPACRHGG VCVRPNKCLC KKGYLGPQCE QVD

Spezifität: Phe18-Asp670

Reinheit: > 90 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1 EU/μg of the protein by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Antigendetails

Target: HHIP (Hedgehog Interacting Protein (HHIP))

Andere Bezeichnung: Hedgehog-interacting protein/HHIP (HHIP Produkte)

Synonyme: fd99f01 Protein, wu:fc52e12 Protein, wu:fd99f01 Protein, zgc:153478 Protein, HIP Protein, Xhip Protein, hip Protein, RGD1564108 Protein, Hhip1 Protein, hedgehog interacting protein Protein, hedgehog interacting protein L homeolog Protein, Hedgehog-interacting protein Protein, hhip Protein, HHIP Protein, hhip.L Protein, Hhip Protein

Hintergrund:

Description: Hip (Hedgehog-interacting protein) is a type I transmembrane protein identified for its ability to bind biologically active Sonic Hedgehog.The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The Hip protein is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.

Name: HHIP,HIP

Gen-ID: 64399

UniProt: Q96QV1

Pathways: Hedgehog Signalweg