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MECP2 Protein (AA 1-177) (His tag)

MECP2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505031
  • Target Alle MECP2 Proteine anzeigen
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-177
    Spezies
    • 8
    • 3
    • 2
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses MECP2 Protein ist gelabelt mit His tag.
    Sequenz
    Met1-Lys177
    Produktmerkmale
    A DNA sequence encoding theHuman MeCP2 protein (P51608) (Met1-Lys177) was expressed with a N-His .
    Reinheit
    >95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MECP2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Andere Bezeichnung
    MeCP2 (MECP2 Produkte)
    Synonyme
    AUTSX3 Protein, MRX16 Protein, MRX79 Protein, MRXS13 Protein, MRXSL Protein, PPMX Protein, RS Protein, RTS Protein, RTT Protein, 1500041B07Rik Protein, BB130002 Protein, D630021H01Rik Protein, Mbd5 Protein, WBP10 Protein, wu:fk96a04 Protein, zgc:111857 Protein, methyl-CpG binding protein 2 Protein, methyl CpG binding protein 2 Protein, methyl-CpG binding protein 2 S homeolog Protein, MECP2 Protein, Mecp2 Protein, mecp2 Protein, mecp2.S Protein
    Hintergrund

    Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

    Synonym: MeCp-2 protein

    Molekulargewicht
    19 kDa
    UniProt
    P51608
    Pathways
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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