Oncostatin M Receptor Protein (OSMR) (AA 28-740) (Fc Tag)
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- Target Alle Oncostatin M Receptor (OSMR) Proteine anzeigen
- Oncostatin M Receptor (OSMR)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 28-740
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Oncostatin M Receptor Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human OSMR Protein
- Sequenz
- Glu28-Met740
- Produktmerkmale
- Recombinant Human OSMR Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Glu28-Met740.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product OSMR Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Oncostatin M Receptor (OSMR)
- Andere Bezeichnung
- OSMR (OSMR Produkte)
- Synonyme
- OSMRB Protein, PLCA1 Protein, oncostatin M receptor Protein, OSMR Protein, Osmr Protein
- Hintergrund
- OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
- Molekulargewicht
- 107.06 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result.
- Pathways
- JAK-STAT Signalweg, Growth Factor Binding
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