Oncostatin M Receptor Protein (OSMR) (AA 28-735) (His tag)
-
- Target Alle Oncostatin M Receptor (OSMR) Proteine anzeigen
- Oncostatin M Receptor (OSMR)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 28-735
-
Spezies
- Hund
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Oncostatin M Receptor Protein ist gelabelt mit His tag.
- Verwendungszweck
- Canine OSMR Protein
- Sequenz
- Glu28-Pro735
- Produktmerkmale
- Recombinant Canine OSMR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Pro735.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product OSMR Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- Oncostatin M Receptor (OSMR)
- Andere Bezeichnung
- OSMR (OSMR Produkte)
- Synonyme
- OSMRB Protein, PLCA1 Protein, oncostatin M receptor Protein, OSMR Protein, Osmr Protein
- Hintergrund
- OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
- Molekulargewicht
- 81.73 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A8I3MI11
- Pathways
- JAK-STAT Signalweg, Growth Factor Binding
-