FCN1 Protein (AA 30-326) (His tag)

Produktnummer ABIN7504333

Produktdetails

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-326

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses FCN1 Protein ist gelabelt mit His tag.

Verwendungszweck: Human ficolin 1/FCN1 Protein

Sequenz: Ala30-Ala326

Produktmerkmale: Recombinant Human ficolin 1/FCN1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala30-Ala326.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, 350 mM NaCl, 200 mM Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Andere Bezeichnung: ficolin 1 (FCN1 Produkte)

Synonyme: FCNM Protein, FCNB Protein, FCN2 Protein, FCN1 Protein, ficolin 1 Protein, ficolin (collagen/fibrinogen domain containing) 1 Protein, ficolin-1 Protein, FCN1 Protein, Fcn1 Protein, LOC100069029 Protein

Hintergrund: The ficolins are members of a recently discovered family of host innate opsonins that can activate the lectin pathway of complement. The ficolins bind many ligands, although they are typically described as binding acetylated sugars. Ficolin-1 is the least-described of the Ficolins and is expressed by monocytes, granulocytes, and in the lungs. Ficolin-1 is found circulating at low concentrations in serum but is regarded primarily as a secretory molecule that exerts its function locally in inflamed tissues.

Molekulargewicht: 33.11 kDa. Due to glycosylation, the protein migrates to 34-38 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_001994

Pathways: Komplementsystem