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C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His-DYKDDDDK Tag)

CLEC4M Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Produktnummer ABIN7504305
  • Target Alle C-Type Lectin Domain Family 4, Member M (CLEC4M) Proteine anzeigen
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 71-399
    Spezies
    • 8
    • 1
    Human
    Quelle
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    His-DYKDDDDK Tag
    Verwendungszweck
    Human CLEC4M/CD299 Protein
    Sequenz
    Gln71-Glu399
    Produktmerkmale
    Recombinant Human CLEC4M/CD299 Protein is expressed from HEK293 with His tag and Flag tag at the N-terminus.It contains Gln71-Glu399.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CLEC4M Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    Andere Bezeichnung
    CLEC4M (CLEC4M Produkte)
    Synonyme
    CD209L Protein, CD299 Protein, DC-SIGN2 Protein, DC-SIGNR Protein, DCSIGNR Protein, HP10347 Protein, L-SIGN Protein, LSIGN Protein, CD209B Protein, C-type lectin domain family 4 member M Protein, CLEC4M Protein
    Hintergrund
    CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance.
    Molekulargewicht
    39.81 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
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