Prokineticin Receptor 1 Protein (PROKR1)
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- Target Alle Prokineticin Receptor 1 (PROKR1) Proteine anzeigen
- Prokineticin Receptor 1 (PROKR1)
- Protein-Typ
- Synthetic
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human PROKR1 full length protein-synthetic nanodisc
- Produktmerkmale
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product PROKR1 Protein
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- Applikationshinweise
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Kommentare
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- Prokineticin Receptor 1 (PROKR1)
- Andere Bezeichnung
- PROKR1 (PROKR1 Produkte)
- Synonyme
- EG-VEGFR1 Protein, Gpr73 Protein, Pkr1 Protein, GPR73 Protein, GPR73a Protein, PKR1 Protein, ZAQ Protein, PROKR1 Protein, prokineticin receptor 1 Protein, Prokr1 Protein, PROKR1 Protein
- Hintergrund
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GPR73, GPR73a, PK-R1, PKR1, ZAQ
Description: This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016] - Molekulargewicht
- The human full length PROKR1 protein has a MW of 44.6 kDa
- UniProt
- Q8TCW9
- Pathways
- Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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