C5AR1 Protein
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- Target Alle C5AR1 Proteine anzeigen
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Protein-Typ
- Synthetic
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human C5AR1 full length protein-synthetic nanodisc
- Produktmerkmale
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product C5AR1 Protein
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Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) protein (GST tag)
C5AR1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Complement Component 5a Receptor 1 (C5AR1) (AA 241-350) protein (GST tag)C5AR1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) protein (Strep Tag)Crystallography grade C5AR1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Complement Component 5a Receptor 1 (C5AR1) (AA 1-351) protein (Strep Tag)Crystallography grade C5AR1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Complement Component 5a Receptor 1 (C5AR1) protein (Myc-DYKDDDDK Tag)C5AR1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Applikationshinweise
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Kommentare
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Andere Bezeichnung
- C5AR1 (C5AR1 Produkte)
- Synonyme
- C5A Protein, C5AR Protein, C5R1 Protein, CD88 Protein, C5aR Protein, C5r1 Protein, Cd88 Protein, D7Msu1 Protein, GPR77 Protein, complement C5a receptor 1 Protein, complement component 5a receptor 1 Protein, C5AR1 Protein, C5ar1 Protein, c5ar1 Protein
- Hintergrund
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C5A, C5AR, C5R1, CD88
Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).[UniProtKB/Swiss-Prot Function] - Molekulargewicht
- The human full length C5AR1 protein has a MW of 39.3 kDa
- UniProt
- P21730
- Pathways
- Komplementsystem
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