Claudin 4 Protein (CLDN4)

Produktnummer ABIN7491600

Produktdetails

Target: Claudin 4 (CLDN4)

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human CLDN4 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Claudin 4 (CLDN4)

Andere Bezeichnung: CLDN4 (CLDN4 Produkte)

Synonyme: CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein

Hintergrund: CPE-R, CPER, CPETR, CPETR1, hCPE-R, WBSCR8
Description: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]

Molekulargewicht: The human full length CLDN4 protein has a MW of 22.1 kDa

UniProt: O14493

Pathways: Hepatitis C