Claudin 4 Protein (CLDN4) (mFc Tag)

Produktnummer ABIN7491287

Produktdetails

Target: Claudin 4 (CLDN4)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Claudin 4 Protein ist gelabelt mit mFc Tag.

Verwendungszweck: Recombinant human CLDN4 (145-157) Protein with C-terminal mouse Fc tag

Spezifität: CLDN4 (Gln145-Lys157) mFc (Pro99-Lys330)

Produktmerkmale: Extracellular Domain Protein

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Claudin 4 (CLDN4)

Andere Bezeichnung: CLDN4 (CLDN4 Produkte)

Synonyme: CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein

Hintergrund: CPE-R, CPER, CPETR, CPETR1, hCPE-R, WBSCR8
Description: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]

Molekulargewicht: predicted molecular mass of 27.7 kDa after removal of the signal peptide. The apparent molecular mass of CLDN4(145-157)-mFc is 25-35 kDa due to glycosylation.

UniProt: O14493

Pathways: Hepatitis C