GPR77 Protein
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- Target Alle GPR77 Proteine anzeigen
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
- Protein-Typ
- Synthetic
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human C5AR2 full length protein-synthetic nanodisc
- Produktmerkmale
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GPR77 Protein
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- Applikationshinweise
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Kommentare
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
- Andere Bezeichnung
- C5AR2 (GPR77 Produkte)
- Synonyme
- GPR77 Protein, C5L2 Protein, GPF77 Protein, E030029A11Rik Protein, Gpr77 Protein, complement component 5a receptor 2 Protein, C5AR2 Protein, C5ar2 Protein
- Hintergrund
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C5L2, GPF77, GPR77
Description: This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] - Molekulargewicht
- The human full length C5AR2 protein has a MW of 36.1 kDa
- UniProt
- Q9P296
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